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Biomarkers for antioxidant defense and oxidative damage; principles and practical applications.

9780813815350

Biomarkers for antioxidant defense and oxidative damage; principles and practical applications.

Ed. by Giancarlo Aldini et al.

Wiley-Blackwell

2010

363 pages

$199.95

Hardcover

RB170

Scientists know that oxidative damage is associated with aging and with various chronic diseases such as diabetes and Alzheimer's disease, but they do not know whether it is the cause or the effect. Either way, however, scientists need to be able to identify and measure oxidative damage. Here chemists, pharmacologists, and other researchers describe the principles behind current methods for measuring antioxidant activity and oxidative stress and their practical applications in specific health situations. Among their topics are enzymatic antioxidant defense, the isoprostanes as accurate markers and potent mediators of oxidant injury in vivo, hydroxyoctadecadienoic acid (HODE) as a marker of linoleic acid oxidation, the immunochemical detection of lipid peroxidation-specific epitopes, covalent modifications of albumin Cys34 as a biomarker of mild oxidative stress, and exocyclic DNA adducts as biomarkers of antioxidant defense and oxidative stress.

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Publication:SciTech Book News
Article Type:Book review
Date:Dec 1, 2010
Words:168
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