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Being overweight decreases rates of success in IVF.

NEW ORLEANS -- Overweight is a significant risk factor for poor in vitro fertilization success rates, particularly in African American women, according to the results of a new study,

"It is highly recommended that patients be encouraged to lose weight," advised Dr. Mohamed Mitwally, who presented the findings at the annual meeting of the American Society for Reproductive Medicine.

There is conflicting evidence in the literature regarding the impact of obesity on in vitro fertilization (IVF) success rates, said Dr. Mitwally of Wayne State University, Detroit. But many previous studies have not controlled for confounding risk factors, he said.

His study analyzed 193 consecutive patients undergoing IVF, 161 white and 32 black patients. After controlling for confounding factors, patients with a body mass index (BMI) of 25 kg/[m.sup.2] or less had a clinical pregnancy rate of 51% per cycle, compared with a rate of 35% in patients with higher BMIs. Overweight had a negative impact in both white and black women, but it was more pronounced in the latter group, said Dr. Mitwally. Overweight white women had a pregnancy rate of 38%, compared with a rate of 50% in those who were normal weight, while overweight black women had a pregnancy rate of 19%, compared with 67% in those who were normal weight.

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Title Annotation:Women's Health; in vitro fertilization
Author:Johnson, Kate
Publication:Family Practice News
Article Type:Brief article
Geographic Code:1U7LA
Date:Dec 15, 2006
Previous Article:Unexplained infertility may not warrant treatment.
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