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Avigen obtains United States patent.

Avigen, Inc. (Alameda, CA) has patented a method for using recombinant adeno-associated virus virions for delivery of DNA molecules to muscle cells and tissue. The invention allows for the direct, in vivo injection of recombinant adeno-associated virus virions into muscle tissue, e.g., by intramuscular injection, as well as for the in vitro transduction of muscle cells which can subsequently be introduced into a subject for treatment. The invention provides for sustained, high-level expression of the delivered gene and for in vivo secretion of the therapeutic protein from transduced muscle cells such that systemic delivery is achieved. (US 6,391,858)
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Comment:Avigen obtains United States patent.(Brief Article)
Publication:BIOTECH Patent News
Article Type:Brief Article
Geographic Code:1USA
Date:May 1, 2002
Words:101
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