Printer Friendly

Atrial fibrillation's impact much worse in women than in men; cardiovascular mortality.

VIENNA -- Atrial fibrillation is a far more powerful risk factor for both stroke and cardiovascular death in women than in men, according to new data from the Copenhagen City Heart Study

The Danish epidemiologic study is a population-based cohort study in which 29,310 adult residents of Copenhagen, including 15,206 with no history of stroke at enrollment, have been followed for a total of 137,391 person-years to date.

During that period, 166 men and 110 women developed documented atrial fibrillation (AF). Of the 635 first-ever strokes that occurred during follow-up, 35 occurred in participants with AF, of whom 22 were women, Dr. Jens Friberg reported at the annual congress of the European Society of Cardiology.

The risk of a first stroke was determined to be 7.8-fold greater in women with AF than in those without the arrhythmia after adjustment for age, diabetes, hypertension, acute MI, left ventricular hypertrophy, and smoking. In contrast, the adjusted risk of stroke in men with AF was 1.7-fold greater than in men without AE That means the independent impact of AF upon stroke risk was 4.6-fold greater in women than in men, said Dr. Friberg of Bispebjerg University Hospital, Copenhagen.

Cardiovascular death has occurred in 1,122 Copenhagen City Heart Study participants, including 28 women and 35 men with AE The adjusted risk of cardiovascular death was 4.4-fold greater in women with AF than in those without it, and 2.2-fold greater in men with AF than in those without it. Thus, the independent effect of AF upon risk of cardiovascular death was twice as great in women as in men.

It's unclear why. One speculation is that since AF is considerably more prevalent among men, it may be that in order for a woman to develop AF she needs to have a sicker heart than men with the arrhythmia in ways that have not yet been identified, the cardiologist said.
COPYRIGHT 2003 International Medical News Group
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2003 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Author:Jancin, Bruce
Publication:Internal Medicine News
Date:Oct 1, 2003
Words:322
Previous Article:Medicare will cover LVRS for certain patient groups, based on NETT survival data: some critics say criteria are too narrow. (lung volume reduction...
Next Article:Supplemental Vitamin E linked to heart failure; effect appears specific to CHF. (congestive heart failure).
Topics:


Related Articles
Atrial fib in elderly women tied to higher von Willebrand factor. (Same Result Not Seen in Men).
December is peak period for atrial fib cases. (Possible Culprits: Infections, More Alcohol).
Panel backs losartan for cutting risk of stroke. (In Hypertensive Patients with LVH).
Atrial fibrillation linked to poor cardiovascular outcomes.
Stroke risk with atrial fib higher in women.
Watchman heart device lowers stroke risk in atrial fibrillation patients.
Women with atrial fibrillation more likely then men to face stroke, death risk.

Terms of use | Privacy policy | Copyright © 2021 Farlex, Inc. | Feedback | For webmasters |