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Ardelyx Study of Tenapanor for IBS-C Hits Demonstrates Ability to Normalize Bowel Function.

M2 PHARMA-October 12, 2017-Ardelyx Study of Tenapanor for IBS-C Hits Demonstrates Ability to Normalize Bowel Function


- Fremont, California-based cardio, renal, and gastrointestinal disease therapeutics developer Ardelyx, Inc. (NASDAQ: ARDX) has reported positive results from T3MPO-2, its second Phase 3 study of tenapanor for irritable bowel syndrome with constipation (IBS-C), the company said.

The study hit statistical significance for the primary endpoint and all secondary endpoints evaluated for the topline results and demonstrated the ability to normalize bowel movements.

The primary endpoint, the combined responder rate for six of 12 weeks, showed that a greater proportion of tenapanor-treated patients compared to placebo-treated patients (36.5% vs. 23.7%, p

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Publication:M2 Pharma
Date:Oct 12, 2017
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