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Apoptosis, Genomic Integrity and Cancer: An Introduction to Interacting Molecules.


Apoptosis, genomic integrity, and cancer; an introduction to interacting molecules.

Van Lancker, Julien L.

Jones & Bartlett


422 pages




Lancker (emeritus pathology, laboratory medicine, and radiation oncology; U. of California-Los Angeles) reviews new insights into cancer pathogenesis that emerged during the last decades of the 20th century, focusing especially on apoptosis and the loss of genomic integrity. Rather than provide details of such aspects as the pathways of cell replication, DNA repair, or programmed cell death, he explores how such knowledge has impacted modern concepts of cancer pathogenesis. His topics include agents that trigger apoptosis, cell cycle checkpoints, tumor transforming growth factors and cancer, and transcription factors and cancer.

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Publication:SciTech Book News
Article Type:Book Review
Date:Mar 1, 2006
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