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Antioxidant Pycnogenol Effective in Improving Symptoms of Mild Cognitive Impairment, New Research Shows.

M2 PHARMA-August 6, 2018-Antioxidant Pycnogenol Effective in Improving Symptoms of Mild Cognitive Impairment, New Research Shows


- A new peer-reviewed study shows that daily supplementation with the natural super-antioxidant Pycnogenol (pic-noj-en-all) can be instrumental in improving the symptoms of Mild Cognitive Impairment (MCI), a potential risk factor for early onset dementia and other degenerative cognitive conditions.

The study, published in Minerva Medica, tested 87 men between the ages of 55 and 75 who showed signs of MCI.

Researchers administered a Mini-Mental State Examination (MMSE) 30-point questionnaire to determine the level of cognitive impairment for each individual.

Participants supplemented with 150mg (three 50mg capsules) of Pycnogenol daily for eight weeks and their MMSE scores were re-evaluated at the end of the study.

All study participants followed a standard management routine including healthy sleep habits, regular exercise, and low sodium and low sugar meals.

Results show that along with these standard management practices, study participants who supplemented with Pycnogenol had an 18 percent improvement of their MMSE scores, including improvements in the following areas:

Significant enhancement of ability to remember friends and family (31.3 percent improvement with Pycnogenol vs. 0 percent improvement control).

Improvement of remembering where things are (39.4 percent improvement with Pycnogenol vs. 6.5 percent improvement control group).

Increase of ability to learn new gadgets and technology (24.1 percent improvement with Pycnogenol vs. 3.3 percent improvement control).

Greater ability to manage money and finances (39.4 percent improvement with Pycnogenol vs. 12.5 percent improvement control).

Significant improvement of ability to deal with people (19.4 percent improvement with Pycnogenol[R] vs. 7.6 percent control).

In addition, researchers found that the participants who supplemented with Pycnogenol[R] also experienced a 16 percent reduction in oxidative stress.

This new study builds upon previous research supporting the benefits of Pycnogenol for cognitive health improvement.

A study conducted in 20152 and published in the Journal of Neurosurgical Sciences showed that Baby Boomers (ages 55+) experienced increased overall cognitive performance, including for memory, attention and daily decision-making.

In addition, a 2008 study in the Journal of Psychopharmacology found that Pycnogenol[R] helps improve numerical working memory as well as spatial memory in seniors.

Pycnogenol is a powerful super-antioxidant shown in decades of research to boost blood circulation and act as a natural anti-inflammatory. Pycnogenol helps endothelial cells produce more nitric oxide (NO) which has multiple effects on brain function.

Initially, NO increases blood flow, which improved oxygenation and the transport of nutrients to brain cells. NO regulates neuronal functions and thus contributes to processing signals inside the brain. In addition, NO helps modulate key neurotransmitters such as dopamine, serotonin and norepinephrine.

This new study supports previous research examining Pycnogenol's benefits for reducing venous conditions and managing jet lag symptoms.

Pycnogenol is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France and is found to contain a unique combination of procyanidins, bioflavonoids and phenolic acids, which offer extensive natural health benefits.

The extract has been widely studied for the past 40 years and has more than 420 published studies and review articles ensuring safety and efficacy as an ingredient.

Currently, Pycnogenol is available in more than 1,000 dietary supplements, multi-vitamins and health products worldwide.

Horphag Research (USA) Inc., based in Hoboken, New Jersey, is the North American distributor for Pycnogenol (pic-noj-en-all) brand French maritime pine bark extract and Robuvit, French oak wood extract on behalf of Horphag Research.

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Publication:M2 Pharma
Date:Aug 6, 2018
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