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Antigen presenting cells; from mechanisms to drug development.


Antigen presenting cells; from mechanisms to drug development.

Ed. by Harald Kropshofer and Anne B. Vogt.



611 pages




This handbook highlights recent evidence that antigen presenting cells (APCs) are critical regulators in the interplay between the innate and adaptive aspects of the human immune system. The handbook is structured in a way to allow access to a broad readership of biochemists, immunologists, and scientists with experience in drug development. Coverage encompasses basic introductory aspects through details for advanced specialists, with material on all cell types involved in antigen presentation. Chapters are in sections on antigen presentation in the immune system, molecular mechanisms of antigen processing, antigen presenting cells' ligands recognized by T- and Toll-like receptors, the repertoire of antigen presenting cells, and antigen presenting cells as drug targets. A glossary is included. Kropshofer and Vogt work in immunology at F. Hoffman-La Roche.

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Publication:SciTech Book News
Article Type:Book Review
Date:Dec 1, 2006
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