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Alexion receives patent covering cloned pig gene which could prevent hyperacute rejection in xenotransplantation.

Alexion Pharmaceuticals, Inc., New Haven, CT, announced the US Patent and Trademark Office has issued a patent a covering the company's cloned pig gal transferase gene. Gal transferase is responsible for synthesis of the cell-bound sugars that are targets of rejection by the human immune system, Alexion says. The cells are believed to be largely responsible for the phenomenon of hyperacute rejection of animal organs transplanted into human recipients. The patent was issued to the Austin Research Institute of Victoria, Australia, and is licensed worldwide exclusively to Alexion.

Contact: Leonard Bell - (203) 776-1790
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Publication:Transplant News
Geographic Code:1USA
Date:Nov 30, 1998
Words:93
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