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Airway inflammation and asthma.

Experts estimate that one percent of the pet cat population is affected by feline asthma and chronic bronchitis. Both conditions are chronic inflammatory diseases of the lower airway that can lead to irreversible 11 image called airway remodeling. Presently, bronchoalveolar lavage fluid (BALF) analysis is the only diagnostic test readily available in a clinical setting to determine the type of inflammatory cell present in the lower airways.

This study ("Subclinical airway inflammation despite high-dose oral corticosteroid therapy in cats with lower airway disease," in Journal of Feline Medicine and Surgery, 2011) is a retrospective evaluation of 10 cats meeting the appropriate criteria for the study.

The goal was to determine the correlation between the resolution of clinical signs in cats receiving oral glucocorticoids with the resolution of inflammation based on l ALF cytology. The findings showed that 70 percent of the cats diagnosed with asthma chronic bronchitis that had resolution of clinical signs (cough, wheeze or episodic respiratory distress) with concurrent high-dose glucocorticoid therapy still had evidence of persistent airway inflammation based on BALF cytology. The results support the statement that caution should be used when equating absence of clinical signs with the at; of airway inflammation. Premature tapering of glucocorticoids based on absence of clinical signs in cats with subclinical inflammation could be detrimental in the long run. udy ("Radical excision with five-centimeter margins for treatment of feline injt as a means to achieving an improved outcome in the treatment of injection-site sarcomas in cats.

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Please note: Some tables or figures were omitted from this article.

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Title Annotation:SHORT TAKES
Publication:Cat Watch
Date:Feb 1, 2012
Words:257
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