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Adult HIV treatment guidelines updated.

On April 7 the U.S. guidelines for antiretroviral treatment were updated to reflect new information on drug interactions and toxicities, and to include a new table on expanded access to antiretrovirals not yet approved (currently the only one available through such a program is tipranavir). The current official U.S. HIV guidelines are always online at the AIDSinfo site published by the U.S. Department of Health and Human Services, (you need to click on the proper category listed on the left of the page, then click again to download the document you want in the format desired--usually PDF). [Note: now that the nonocccupational exposure document (what to do if the condom breaks, etc.) is official, it is available on this site as well.]

On April 8 the U.S. Food and Drug Administration (FDA) published the following description of the changes made in the current revision:
 The Guidelines for the Use of Antiretroviral
 Agents in HIV-Y-Infected Adults and Adolescents
 has been revised to include up-to-date
 drug information, including updated information
 on nevirapine hepatotoxicity risks, the
 interaction between rifampin and ritonavirboosted
 saquinavir, new pregnancy data for
 efavirenz, and new contraindications and
 warnings for ritonavir and lopinavir/ritonavir
 use. Also included in the updated document is
 a new table, Table 30, providing information
 on the tipranavir expanded access program.

 All changes to the document are highlighted
 in yellow.

 The updated guidelines document is available
 at the AIDSinfo Web site at:
 You can view, order hard copies of the
 guidelines, or request them by email at the
 web site.

 The AIDSinfo website is also a useful source
 of other information related to HIV/AIDS,
 including other treatment and prevention
 guidelines, downloadable databases for PDAs
 (Personal Digital Assistants), and HIV/AIDS--related
 clinical trials information.
COPYRIGHT 2005 John S. James
No portion of this article can be reproduced without the express written permission from the copyright holder.
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Publication:AIDS Treatment News
Geographic Code:1USA
Date:Mar 25, 2005
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