Addressing the hazards of post-flood mold to public health.
1. Collection and preservation of a variety of molds from structures inundated by flood-water.
2. Synthesis of a limited number of novel formamide fungicides. Novel formamide fungicides have an unknown and potentially new mode of anti-fungal action. They may become instrumental in overcoming resistance to the currently used fungicides.
3. Confirmation (verification) of the structures via spectroscopic methods (IR, NMR, MS) and elemental analysis.
4. Biological (antifungal) testing of the newly synthesized compounds in vitro against molds from structures inundated by flood-water.
Results: The results of the research will provide data for mapping structure-activity relationships among novel formamide fungicides. The results may also have some practical value if novel fungicides will be capable of providing a lasting and efficient control of dangerous molds.
Supported by the Great Plains Center for Community Research and Service as funded by the US Department of Education Grant Award P1 16Z100151
Braden A. Burckhard, Luke W. Uran, Lioudmila I. Bobyleva, Mikhail M. Bobylev *
Minot State University, Division of Science, Minot, ND 58707
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|Title Annotation:||Professional Communications|
|Author:||Burckhard, Braden A.; Uran, Luke W.; Bobyleva, Lioudmila I.; Bobylev, Mikhail M.|
|Publication:||Proceedings of the North Dakota Academy of Science|
|Article Type:||Brief article|
|Date:||Apr 1, 2012|
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