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Acetaminophen and asthma.

The Question: Does prenatal and early infancy acetaminophen exposure increase the chances of developing asthma?

The Study: A meta-analysis of 11 observational studies looked at acetaminophen use and the subsequent development of asthma. A careful analysis of each study protocol was done.

The Results: The results were inconsistent. The authors found that three studies did show a relationship, but this almost totally disappeared when respiratory tract infections in the mother and child were taken into account. The authors concluded there wasn't enough information to recommend changing any guidelines.

Comment: Not all studies result in changes in what's considered best treatment. This study supports the safety of prenatal and early infancy use of acetaminophen.

Read More: Archives of Disease in Childhood, 01/15

Richard J. Sagall, MD, Editor

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Title Annotation:In the Literature; risk of developing asthma in infants with prenatal exposure to acetaminophen
Author:Sagall, Richard J.
Publication:Pediatrics for Parents
Article Type:Brief article
Geographic Code:1USA
Date:Mar 1, 2014
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