AACC Award for Outstanding Scientific Achievements by a young investigator.
Dr. Garg did his postdoctoral training at the New York Medical College in Pharmacology and Cell Biology under the direction of Dr. Aviv Hassid, currently Brownstein Professor of Cardiovascular Physiology at the University of Tennessee. During his postdoctoral training, Dr. Garg received an American Heart Association Fellowship to study the role of nitric oxide and atrial natriuretic factor in the regulation of smooth muscle cell growth. Along with his mentor, he demonstrated that nitric oxide and cyclic GMP inhibit smooth muscle and mesangial cell growth and proliferation induced by serum and various growth factors, such as platelet-derived growth factor, epidermal growth factor, insulin-like growth factor, and fibroblast growth factor. They also demonstrated that nitric oxide exerts its effect both through and independent of cyclic GMP. At the New York University Medical Center, Dr. Garg, along with Dr. Mylar Bansinath, demonstrated the role of nitric oxide in the regulation of glial cell proliferation; he was awarded FIDIA Research Foundation Travel Award to present his findings at a symposium entitled, "Excitatory Amino Acids", held in 1992 at Yosemite Park, California.
Dr. Garg completed his Clinical Chemistry Fellowship at the University of Minnesota Medical School in Minneapolis under the direction of Drs. John Eckfeldt and Michael Tsai. After completing the fellowship, he continued his stay at the University of Minnesota Medical School in Minneapolis as an Assistant Professor. Along with Dr. Eckfeldt as the Principal Investigator, Dr. Garg contributed to NHLBI-funded research grants, "Family Heart Study-Central Laboratory" and "Hypertension Genetics-Biochemistry Laboratory" as a co-investigator. The research group studied various cardiovascular risk factors, including homocysteine, lipids, factor V, and apolipoprotein E. During his stay at the University of Minnesota Medical School, Dr. Garg was awarded a VanSlyke Society Research grant entitled, "Approaches to Identify Homocystinuria Heterozygotes" from the AACC. He received the Richard Marshall travel award from the Midwest Section of Clinical Chemistry and a travel award from the AACC to present his findings. In addition, he developed several methods for clinical use, including a molecular assay for the diagnosis of hereditary hemochromatosis, an assay for cystathionine [beta]-synthase in cultured fibroblasts, a methionine loading test for the diagnosis of heterozygosity of homocystinuria, and a method for molecular diagnosis of sickle cell disease using microextracted DNA from Guthrie cards.
Dr. Garg has published >40 peer-reviewed research papers and has presented his work in various national and international meetings. His research work has been cited in >1000 publications, including several citations by Nobel Laureate Dr. John Vane. He has peer-reviewed research papers for several scientific journals, including Clinical Chemistry, Neuroscience, and Life Sciences. Dr. Garg is certified in clinical chemistry by the American Board of Clinical Chemistry and the American Society of Clinical Pathology. His major research interest is in the development of methods for clinical laboratories.
Compiled by David E. Bruns, Editor (firstname.lastname@example.org)
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|Title Annotation:||The Clinical Chemist|
|Author:||Bruns, David E.|
|Date:||Jul 1, 1998|
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