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AACC Award for Outstanding Contributions to Clinical Chemistry in a selected area of research.

Larry J. Kricka, PhD, will receive the 26th annual award, sponsored by Roche Diagnostic Systems. Dr. Kricka is Professor of Pathology and Laboratory Medicine at the University of Pennsylvania and Director of the General Chemistry Laboratory at the Hospital of the University of Pennsylvania. He received his BA and D Phil degrees in chemistry from York University, England, and after completing postdoctoral training at the University of Liverpool, England, he joined the faculty in the Department of Clinical Chemistry and Wolfson Research Laboratories at the University of Birmingham, England, where he was a Reader in Clinical Chemistry. Dr. Kricka is a fellow of the Royal College of Pathologists and the Royal Society of Chemistry, and a member of the Association of Clinical Biochemists.

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Dr. Kricka has played an active role in the AACC and is currently a member of the Board of Directors of the AACC, and a member of the Editorial Board of the association's journal, Clinical Chemistry. In the Philadelphia Section, he has held the positions of chair and membership chair, and also participates in the activities of the Northeast Alliance. He was chair of the Symposium Committee for C1iniChem '91, '93, and '94, and was Chair of CliniChem '97. At the divisional level, Dr. Kricka has served on the Clinical Diagnostics and Immunology Division Committee; at the national level, he chaired the Oak Ridge Conference Committee and was a member of the Meetings Management Group and the Board of Editors, AACC Press. Previously, he was a member of the Endo/LIP Committee and Chair of the Symposium Committee for the 1993 National Meeting held in New York.

Dr. Kricka is also active at the international level; he serves on the International Scientific Program Committee of the International Symposium on Bioluminescence and Chemiluminescence, and was recently appointed Chair of the Committee on Advanced Technologies of the International Federation of Clinical Chemistry (IFCC).

His research interests include micromachined analytical systems, the analytical applications of bioluminescence and chemiluminescence, nonisotopic immunoassays, and heterophile antibodies. His work in chemiluminescence originated at the Wolfson Research Laboratories, Birmingham, England. Together with Tom Whitehead, Gary Thorpe, and other members of the Wolfson team, he developed the enhanced chemiluminescent detection reactions for peroxidase labels, which were subsequently commercialized in conjunction with Dr. Ed Foottit at the British Technology Group, London, England. Further studies on the application of chemiluminescent reactions and stabilized adamantyl dioxetane substrates for alkaline phosphatase labels in immunoassay and DNA analysis were undertaken in collaboration with Dr. Irena Bronstein at Tropix, in Bedford, Massachusetts.

During the past decade, Dr. Kricka's ongoing collaboration with Dr. Peter Wilding, and more recently with Dr. Paolo Fortina, has led to major advances in the development and application of micromachined devices in clinical analysis. Silicon microchips have been devised and tested for a diverse range of analytical and preparative techniques, including sperm motility, in vitro fertilization, immunoassay, cell isolation, and different types of nucleic acid analyses (PCR, DOP-PCR, and LCR). His current work is directed towards the development of fully integrated microchips ("lab-on-achip") for PCR-based assays.

Dr. Kricka has lectured extensively, has published >250 papers and review articles, and has authored/edited 12 books. He is Editor-in-Chief of the Journal of Bioluminescence and Chemiluminescence, Editor of the Journal of Immunoassay, a member of the editorial boards of Clinical Chemistry, Analytical Biochemistry, and Talanta, and an invited reviewer for many prestigious scientific journals.

Dr. Kricka's previous awards and honors include the Society of Analytical Chemistry Silver Medal (Royal Society of Chemistry) (1981), the British Technology Group Academic Enterprise Competition Award (1985), the Department of Trade and Industry, Industry Year Award for Technology Transfer (1986), the Prince of Wales Award for Innovation and Production (1989), the Queens Award for Technological Achievement (1990), the Rank Prize for Opto-Electronics (1991), the Certificate of Honor Award, AACC, New Jersey Section (1995), and the Kubasik Lecture Award, AACC, New York Upstate Section (1997).

Compiled by David E. Bruns, Editor (dbruns@aacc.org)
COPYRIGHT 1998 American Association for Clinical Chemistry, Inc.
No portion of this article can be reproduced without the express written permission from the copyright holder.
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Title Annotation:The Clinical Chemist
Author:Bruns, David E.
Publication:Clinical Chemistry
Date:Jul 1, 1998
Words:659
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