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Zacks.com Expert Watch Highlights the Following Stocks: Imclone, Abgenix, Amgen, Dendreon, and ISTA Pharmaceuticals.


CHICAGO -- Biotechnology holds the keys to the future of your health and your profits. Discover the companies that will change your life and portfolio today. Read the full Experts Watch article with commentary and recommendations on Imclone (NASDAQ NASDAQ
 in full National Association of Securities Dealers Automated Quotations

U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on
:IMCL IMCL International Making Cities Livable
IMCL Inter Marine Container Lines
IMCL International Management Consultants Ltd.
IMCL Indraprastha Medical Corp Ltd (India)
IMCL Imperial Majesty Cruise Line
), Abgenix (NASDAQ:ABGX), Amgen (NASDAQ:AMGN), Dendreon (NASDAQ:DNDN) and ISTA ISTA International Safe Transit Association
ISTA Indiana State Teachers Association
ISTA International Seed Testing Association
ISTA International Sail Training Association
ISTA Information, Science, and Technology Agency (British Columbia) 
 Pharmaceuticals (NASDAQ:ISTA) go to; http://at.zacks.com/?id=101

Here are the highlights from the Experts Watch column:

Each spring the American Society of Clinical Oncologists convenes for the reporting of the most recent data in the battle against cancer. The Experts closely scrutinize the data that comes out of this meeting as it can be incredibly lucrative. In spite of the fact that the AMEX AMEX

See: American Stock Exchange
 Biotech Index is off 14% from its highs in mid-April, the Experts believe there are a number of hot biotech stories that can help round out your portfolio.

According to Dr. Scott and Nadine Wong, editors of the Biotech Stock Report, the biggest story to come out of this year's ASCO ASCO American Society of Clinical Oncology
ASCO Association of Schools and Colleges of Optometry (since 1941; Rockville, Maryland)
ASCO Australian Standard Classification of Occupations
ASCO Automatic Switch Company
 meeting was data on Imclone's (NASDAQ:IMCL) drug, Erbitux. The drug was revealed to improve the efficacy of radiation in the treatment of head and neck cancers. Erbitux is a mouse/human chimeric chi·mer·ic
adj.
1. Relating to a chimera.

2. Composed of parts of different origin.
 monoclonal antibody that targets the human epithelial growth factor receptor A growth factor receptor is a receptor which binds to growth factor. External links
  • MeSH Growth+Factor+Receptors


    
 (EGFR EGFR Epidermal Growth Factor Receptor (a kinase enzyme)
EGFR Estimated Glomerular Filtration Rate
) that is found in normal and cancerous tissue. Imclone is not currently in the Wong's Bioportfolio, but the head and neck cancer theme is very important to their current investment strategies.

Abgenix (NASDAQ:ABGX) and Amgen (NASDAQ:AMGN) presented data together at the ASCO meeting on their EGFR treatment. The company's report on ABX-EGF places it on par with Erbitux, according the Wongs. Specifically, patients in a Phase II clinical trial Noun 1. phase II clinical trial - a clinical trial on more persons than in phase I; intended to evaluate the efficacy of a treatment for the condition it is intended to treat; possible side effects are monitored
phase II
 exhibited a 10% objective response rate, which provided stimulus for a larger Phase III clinical trial Noun 1. phase III clinical trial - a large clinical trial of a treatment or drug that in phase I and phase II has been shown to be efficacious with tolerable side effects; after successful conclusion of these clinical trials it will receive formal approval from the . The Wongs will be looking for that next release of data, but they own both companies in their Bioportfolio.

Dendreon (NASDAQ:DNDN) adopts an alternative approach. The company is working on the development of a cancer vaccine. Interestingly, Dendreon's share price appreciated during the last week of June, after a workshop held by the FDA FDA
abbr.
Food and Drug Administration


FDA,
n.pr See Food and Drug Administration.

FDA,
n.pr the abbreviation for the Food and Drug Administration.
 on Tuesday, June 22, to formulate a strategy on possible alternative standards the agency could use to gauge the effectiveness of drugs to treat prostate cancer. Dendreon did announce it received fast track FDA designation for the use of Provenge in treating asymptomatic metastatic Metastatic
The term used to describe a secondary cancer, or one that has spread from one area of the body to another.

Mentioned in: Coagulation Disorders


metastatic

pertaining to or of the nature of a metastasis.
 androgen-independent prostate cancer, and released data that it improves survival times in patients. The Wongs have a target price of $17.

Lon Juricic, editor of the Biotech Insider, also sees profits to be made in the biotech arena. Specifically, he recently added ISTA Pharmaceuticals (NASDAQ:ISTA) to his portfolio. ISTA's products seek to address serious diseases and conditions of the eye such as vitreous vitreous /vit·re·ous/ (vit´re-us)
1. glasslike or hyaline.

2. vitreous body.


primary persistent hyperplastic vitreous
 hemorrhage, diabetic retinopathy, hyphema, glaucoma, ocular pain and inflammation. ISTA announced FDA approval of Istalol for glaucoma, which is the company's second FDA approval; the company announced FDA approval for Vitrase as a spreading agent in May. Because of the company's successful navigation of the FDA system, its undiscovered status, and the numerous positive catalysts, Juricic believes ISTA represents a major opportunity for risk adverse biotech investors.

Read the full report with insight from the experts at Zacks.com: http://at.zacks.com/?id=102

About Zacks Experts Watch

To be a successful investor you need professional advice. Experts who know what they're talking about and can help you achieve your financial goals in good markets...and especially in bad ones will help you improve your portfolio. That is why Zacks Investment Research Zacks Investment Research

A firm that compiles earnings estimates and brokerage firm investment recommendations for thousands of publicly traded firms.
 has assembled the best investment experts in the business to offer their powerful advice ton on all the major investment topics.

Recommendations from Experts Highlighted in FREE Investment Newsletter

The best way to tap into the powerful advice from these experts is through our free weekly e-mail newsletter, "Profit from the Pros". Each week we highlight several experts with a track record of beating the street in this e-mail newsletter. Get your free subscription to "Profit from the Pros" at: http://at.zacks.com/?id=103

About Zacks

Zacks.com is a property of Zacks Investment Research, Inc., which was formed in 1978 to compile, analyze, and distribute investment research to both institutional and individual investors. The guiding principle behind our work is the belief that investment experts, such as brokerage analysts and investment newsletter writers, have superior knowledge about how to invest successfully. Our goal is to unlock their profitable insights for our customers. And there is no better way to enjoy this investment success, than with a FREE subscription to "Profit from the Pros" weekly e-mail newsletter. For your free newsletter, visit http://at.zacks.com/?id=104

Zacks Investment Research is under common control with affiliated entities (including a broker-dealer and an investment adviser), which may engage in transactions involving the foregoing securities for the clients of such affiliates.

Disclaimer: Past performance does not guarantee future results. Investors should always research companies and securities before making any investments. Nothing herein should be construed as an offer or solicitation to buy or sell any security.
COPYRIGHT 2004 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2004, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Jul 1, 2004
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