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Whatman/Schleicher & Schuell Partners with IIM for More Rapid and Accurate Diagnosis of Autoimmune Diseases.


FLORHAM PARK, N.J. -- Whatman/Schleicher & Schuell, a global leader in separations technology, today announced a partnership with Privates Institut fur Immunologie und Molekulargenetik GmbH (IIM IIM Indian Institute of Management (main Management Institutes of India)
IIM Individual Indian Money (US Department of Interior)
IIM Industrial Information Management
), a premier German laboratory that specializes in autoimmune and other clinical diagnostic assays, to develop, manufacture and distribute a protein biochip biochip

Small-scale device, analogous to an integrated circuit, constructed of or used to analyze organic molecules associated with living organisms. One type of theoretical biochip is a small device constructed of large organic molecules, such as proteins, and capable of
 for autoimmune disease autoimmune disease, any of a number of abnormal conditions caused when the body produces antibodies to its own substances. In rheumatoid arthritis, a group of antibody molecules called collectively RF, or rheumatoid factor, is complexed to the individual's own gamma  diagnosis.

Whatman/Schleicher & Schuell's nitrocellulose-coated FAST(R) slides, the industry-leading surface for protein microarray A protein microarray is a piece of glass on which different molecules of protein have been affixed at separate locations in an ordered manner thus forming a microscopic array.  assays, enables comprehensive protein analysis to take place using a single serum sample. Unlike modified glass surfaces, the three-dimensional microporous structure of FAST(R) Slides provides a much larger surface area for protein immobilization Immobilization Definition

Immobilization refers to the process of holding a joint or bone in place with a splint, cast, or brace. This is done to prevent an injured area from moving while it heals.
 that translates to higher binding capacities and higher sensitivity of detection.

"The FAST(R) slides turned out to be an excellent surface for autoimmune diagnostic assays, and the protein microarray expertise of the Whatman/Schleicher & Schuell team was instrumental in developing this powerful diagnostic tool," said Dr. Appelhans, General Manager at IIM. "This chip will enable our laboratories to measure the presence of autoantibodies to various autoantigens associated with different collagenosis and vasculititis-related autoimmune diseases Autoimmune diseases
A group of diseases, like rheumatoid arthritis and systemic lupus erythematosus, in which immune cells turn on the body, attacking various tissues and organs.

Mentioned in: Complement Deficiencies, Premature Menopause
 from a single serum sample. In addition to saving time, the biochip will generate a more complete autoimmune disease profile that will allow physicians to make a better diagnosis."

Expected to launch at the end of 2005, this diagnostic assay product is currently being validated to ensure compliance with the CE guidelines for in-vitro diagnostics.

"IIM's proficiency in the clinical diagnosis of autoimmune diseases has contributed exponentially to our efforts to bring emerging protein microarray technology to the clinical diagnostic market," said Dr. Jens Beator, Project Manager at Whatman/Schleicher & Schuell. "Our collaboration with Prof. Seelig and Dr. Appelhans has produced a result that will add substantial expediency ex·pe·di·en·cy  
n. pl. ex·pe·di·en·cies
1. Appropriateness to the purpose at hand; fitness.

2. Adherence to self-serving means:
 and effectiveness to the routine clinical diagnosis of common autoimmune diseases."

About Whatman

Whatman is a global leader in separations technology and is known in the scientific community for providing innovative life science products and solutions. With the acquisition of Schleicher & Schuell, Whatman offers a more comprehensive product range to its customers worldwide and enters the proteomics market with Schleicher & Schuell's core competency A core competency is something that a firm can do well and that meets the following three conditions specified by Hamel and Prahalad (1990):
  1. It provides customer benefits
  2. It is hard for competitors to imitate
  3. It can be leveraged widely to many products and markets.
 in protein chip technologies. For more information visit us at www.whatman.com.
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Copyright 2005, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Aug 8, 2005
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