Vanderbilt University obtains United States patent.Vanderbilt University (Nashville, TN) has patented a composition comprising a nuclear localization Customizing software and documentation for a particular country. It includes the translation of menus and messages into the native spoken language as well as changes in the user interface to accommodate different alphabets and culture. See internationalization and l10n. sequence and a peptide nucleic acid oligomer oligomer /ol·i·go·mer/ (ol´i-go-mer) a polymer formed by the combination of relatively few monomers.
oligomer ( (NLS-PNA). Uses of the composition include, but are not limited to: regulation of gene expression Gene modulation redirects here. For information on therapeutic regulation of gene expression, see therapeutic gene modulation.
. , gene therapy, and the production of pharmaceutical nucleic acids and proteins. In addition, the NLS-PNA is useful for scientific and therapeutic transfection and expression of nucleic acids in cells types that previously were resistant to transfection and therapy including quiescent cells, differentiated cells, embryonic stem cells, and eukaryotic cells with intact nuclear membranes. The NLS-PNA can be combined with a membrane transport sequence (MTS (1) See Microsoft Transaction Server.
(2) (Modular TV System) The stereo channel added to the NTSC standard, which includes the SAP audio channel for special use.
1. MTS - Message Transport System.
2. ) forming a novel compound referred to as an MTS-NLS-PNA wherein the MTS provides transport through the cytoplasmic membrane of a cell. A nuclear targeted peptide nucleic acid oligomer is useful for the treatment of genetic based diseases and diseases that can be treated genetically including heart disease, cancer, cerebrovascular diseases, chronic pulmonary diseases, human immunodeficiency virus human immunodeficiency virus
Human immunodeficiency virus (HIV)
A transmissible retrovirus that causes AIDS in humans. , and other diseases, conditions and disorders. (US 6,623,966)