Using EX/RP to treat OCD.
After a 12-week acute phase, those who responded to three treatment protocols were placed into the discontinuation phase and followed for 12 weeks. The treatment protocols of the 46 responders were EX/RP, n=18; EX/RP plus clomipramine, n=15; clomipramine, n=11; and placebo, n=2. Patients were assessed every 4 weeks by an investigator blinded to treatment protocols (Depress. Anxiety 19:225-33, 2004).
Twelve weeks after discontinuing therapy, the relapse rate for EX/RP and EX/RP plus clomipramine patients was a combined 12%, significantly lower than the 45% relapse rate for patients receiving just clomipramine, the investigators said. Clomipramine patients also had a significantly shorter time to relapse after discontinuing treatment than did the two groups using EX/RP. Dr. Simpson added.
|Printer friendly Cite/link Email Feedback|
|Title Annotation:||Clinical Capsules; obsessive-compulsive disorder; Intensive exposure and response prevention|
|Publication:||Clinical Psychiatry News|
|Article Type:||Brief Article|
|Date:||Sep 1, 2004|
|Previous Article:||Depression: what works best?|
|Next Article:||PTSD and myocardial infarction.|