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Updated Practice Guidelines for the Diagnosis and Monitoring of Thyroid Disease Available Online in Thyroid Journal.

Health/Medical Writers

LARCHMONT, N.Y.--(BUSINESS WIRE)--Feb. 3, 2003

The long-awaited, revised National Academy of Clinical Biochemistry Practice Guidelines, entitled "Laboratory Support for the Diagnosis and Monitoring of Thyroid Disease," are available in their entirety in the January 2003 (Volume 13, Number 1) issue of Thyroid, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com). The issue is available free online at www.liebertpub.com/thy.

The report, written by Laurence M. Demers, Ph.D., and Carole A. Spencer, Ph.D., emphasizes the need for "quality laboratory testing support for the accurate diagnosis and cost-effective management of thyroid disorders."

"These long-awaited guidelines are global consensus guidelines developed from extensive consultation and review by multiple thyroid experts worldwide," says Dr. Spencer, co-editor of the guidelines and a guest editor of the January 2003 issue of Thyroid. "The guidelines are designed to give practicing clinicians and clinical laboratory scientists an overview of the strengths and limitations of the current biochemical and cytological thyroid tests used in clinical practice."

Included in the Practice Guidelines are an overview of pre-analytic factors, a discussion of the importance of the laboratory-physician interface, and a detailed look at the range of thyroid tests available, including measurement of total and free thyroxine (T4) and triiodothyronine (T3), thyroid stimulating hormone, thyroid autoantibodies (thyroid peroxidase, thyroglobulin, and thyrotrophin receptor antibodies), thyroglobulin, calcitonin, the ret proto-oncogene, and urinary iodide. Guidelines for performing fine needle aspiration and cytology, as well as for screening for congential hypothyroidism round out the discussion.

Specific guidelines include the following: thyroid testing of ambulatory or hospitalized patients, of infants and children, and of pregnant patients; clinical utility of TSH assays; clinical uses of TRAb measurement; serum total T4 and total T3 measurements; thyroid hormone binding ratio or "uptake" tests; clinical utility of serum free T3 estimate tests; and levothyroxine replacement therapy for primary hypothyroidism. Tables clearly outline the proper procedures for thyroid testing and the guidelines for interpreting test results.

Thyroid, edited by Terry F. Davies, M.D. , of the Division of Endocrinology, Diabetes & Bone Diseases at Mount Sinai School of Medicine (New York, NY), is an authoritative peer-reviewed journal published monthly in print and online. As the Official Journal of the American Thyroid Association, Thyroid publishes original papers and timely reviews that reflect the rapidly advancing changes in our understanding of thyroid physiology and pathology, from the molecular biology of the cell to clinical management of thyroid disorders. A complete table of contents and free sample issue may be viewed online at www.liebertpub.com/thy.

Mary Ann Liebert, Inc., is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Diabetes Technology & Therapeutics, and Journal of Women's Health. Its biotechnology trade magazine, Genetic Engineering News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 60 journals, books, and newsletters is available at www.liebertpub.com.
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Publication:Business Wire
Date:Feb 3, 2003
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