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Unusual tumor is contagious in dogs.


A type of cancer in dogs is transferred from animal to animal by the exchange of cancer cells, a new study suggests. The results add credence to unusual reports that certain cancers can pass between animals within a species, most notably in Tasmanian devils (SN: 2/4/06, p. 67).

Canine transmissible venereal tumor Canine transmissible venereal tumor (CTVT), also called transmissible venereal tumor (TVT), Sticker tumor and infectious sarcoma is a tumor of the dog and other canids that mainly affects the external genitalia, and is transmitted from animal to animal during  (CTVT CTVT Canine Transmissible Venereal Tumor
CTVT Community TV Trust (UK charity)
CTVT Chaparral Television Trainer
) appears most often in stray dogs. As the name implies, it's considered contagious. However, because cancer generally isn't transmissible transmissible /trans·mis·si·ble/ (trans-mis´i-b'l) capable of being transmitted.

trans·mis·si·ble
adj.
Capable of being conveyed from one person to another.
, scientists puzzled over the identity of the infectious agent. Some researchers have suspected that a cancer-causing virus plays a role.

To investigate CTVT'S cause, Robin Weiss of University College London “UCL” redirects here. For other uses, see UCL (disambiguation).
University College London, commonly known as UCL, is the oldest multi-faculty constituent college of the University of London, one of the two original founding colleges, and the first British
 and his colleagues took tumor and blood samples from 16 dogs identified with the disease. The dogs came from three continents.

They found that in no dog did the tumor's DNA DNA: see nucleic acid.
DNA
 or deoxyribonucleic acid

One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes.
 match that in the animal's blood. However, tumor DNA was identical from dog to dog. It also matched the DNA of 40 other CTVT samples stored in veterinary schools on five continents, suggesting that bits of the same tumor had circulated and grown in dogs around the world.

Further examination suggested that the tumor arose at least 200 years ago in a gray wolf or another dog-related species, Weiss' team reports in the Aug. 4 Cell. Some quality of that tumor enabled it to be transferred between related species by sexual contact, licking, or biting, the group suggests.
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Title Annotation:canine transmissible venereal tumor
Author:Brownlee, Christen
Publication:Science News
Article Type:Brief article
Geographic Code:4EUUK
Date:Aug 26, 2006
Words:233
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