United States : Affymetrix Announces Major Genotyping Project With Kaiser Permanente and the University of California at San Francisco for NIH-Funded Epidemiology Study.Byline: datta03 Affymetrix, Inc. (Nasdaq:AFFX) today announced that the Kaiser Permanente Research Program on Genes, Environment, and Health (RPGEH) and the University of California The University of California has a combined student body of more than 191,000 students, over 1,340,000 living alumni, and a combined systemwide and campus endowment of just over $7.3 billion (8th largest in the United States). at San Francisco (UCSF UCSF University of California at San Francisco ) have entered into an agreement with Affymetrix to support genome-wide analyses of DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. samples from 100,000 Kaiser Permanente members. The members have volunteered for a large-scale research program designed to create a new resource for studying disease, health, and aging. Scientists from the program will use the just-launched Axiom Genotyping Solution, which delivers high-throughput, automated technology and enables researchers to find novel and common genetic variations associated with complex disease. DNA studies will be linked to Kaiser Permanente s electronic health record system, the largest of its kind. Information from health surveys and environmental data will also be analyzed. These resources will give researchers an entirely new platform for studying genetic and environmental influences over time on a wide variety of health conditions, across diverse populations. The program is being funded by a $24.8 million grant from the National Institutes of Health (NIH "Not invented here." See digispeak. NIH - The United States National Institutes of Health. )1, and over the next two years, a significant portion of this amount is expected to be used to purchase the Axiom Genotyping Solution. The Kaiser Permanente RPGEH is a growing resource for scientific research designed to facilitate epidemiologic studies of both genetic and environmental influences on common health conditions, such as heart disease, diabetes, cancer, asthma, mental health disorders, and many others. The NIH grant gives Kaiser Permanente and UCSF an opportunity to utilize a new model for studying human genetics Human genetics A discipline concerned with genetically determined resemblances and differences among human beings. Technological advances in the visualization of human chromosomes have shown that abnormalities of chromosome number or structure are surprisingly , said Kevin King, president and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. of Affymetrix. We greatly value the relationship we have built with the program leaders over the last two years, and we are excited that our technology will be used to help researchers study effective prevention and treatment strategies to improve healthcare and quality of life. The Axiom Solution is configured to continually validate and incorporate the output of large-scale sequencing projects. Initial offerings are designed from public databases of human variations and cover historical HapMap data supplemented by subsequent releases of additional variants. In addition, Affymetrix is screening millions of putative SNPs and insertions/deletions that are being discovered by the 1000 Genomes Project and other sources, and will make these available to researchers using the Axiom Solution. The solution consists of Axiom Array Plates, complete Axiom Reagent Kits, an automated target preparation station developed jointly by Affymetrix and Beckman Coulter, plus the GeneTitan Multi-Channel (MC) Instrument. The GeneTitan MC Instrument integrates a hybridization hybridization /hy·brid·iza·tion/ (hi?brid-i-za´shun) 1. crossbreeding; the act or process of producing hybrids. 2. molecular hybridization 3. oven, fluidics fluidics, branch of engineering and technology concerned with the development of equivalents of various electronic circuits using movements of fluid rather than movements of electric charge. processing, CCD CCD in full charge-coupled device Semiconductor device in which the individual semiconductor components are connected so that the electrical charge at the output of one device provides the input to the next device. imaging device, and analysis software for maximum data reproducibility, user productivity, and scalability. Copyright : Euclid Infotech Pvt. Ltd. Provided by Syndigate.info an Albawaba.com company |
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