United States : $5.5 million grant to Cedars-Sinai Heart Institute for development of cardiac stem cell therapies.Byline: pinto03 A team of Cedars-Sinai Heart Institute stem cell stem cell In living organisms, an undifferentiated cell that can produce other cells that eventually make up specialized tissues and organs. There are two major types of stem cells, embryonic and adult. researchers led by Eduardo Marban, M.D., Ph.D. has been awarded a four-year, $5.5 million grant from the California Institute of Regenerative Medicine (CIRM CIRM Certified in Integrated Resource Management CIRM California Institute for Regenerative Medicine CIRM Comité International Radio-Maritime (International Radio-Medical Center) CIRM Corporate Infrastructure Resource Management ) to fund research leading to clinical trials of new treatments for heart attack patients. The grant will be used to continue Marban's development of cardiac stem cell therapies stem cell therapy Cell therapy Molecular medicine A technology in which a person's own cells–eg, neuronal stem cells are triggered to revert to their primitive embryonic form, then redifferentiate into mature cells of various organs to strengthen and heal damaged heart muscle caused by cardiac arrest cardiac arrest n. Abbr. CA A sudden cessation of cardiac function, resulting in loss of effective circulation. Cardiac arrest A condition in which the heart stops functioning. . The grant is part of a new strategy by the California state stem cell agency aimed at speeding the process of moving medical research from the laboratory to patient care. Generally, it can take a decade or more to develop a new medical treatment to the point of securing federal approval for a clinical trial. The state institute's Disease Team Research Awards, however, are designed to help researchers develop medical theories into treatments tested by clinical trials in four years or less. Marban's team was one of 11 in California to receive a Disease Team Research Award and is the only team focusing on heart disease. Heart disease is the leading cause of death in the United States. According to the Centers for Disease Control, in 2009, an estimated 785,000 Americans will have a first-time heart attack and about 470,000 will have a recurrent attack. Earlier this year, Marban, who is director of the Cedars-Sinai Heart Institute, and his team completed the first procedure in which a patient's own heart tissue was used to grow specialized heart stem cells stem cells, unspecialized human or animal cells that can produce mature specialized body cells and at the same time replicate themselves. Embryonic stem cells are derived from a blastocyst (the blastula typical of placental mammals; see embryo), which is very young that were then injected back into the patient's heart in an effort to repair and re-grow healthy muscle in a heart that had been injured by a heart attack. The minimally-invasive procedure was completed on the first patient on June 26. The Disease Team Award will enable Marban's team to develop other, new stem cell therapies for heart patients, including a potential treatment for patients with advanced heart failure. "The support Cedars-Sinai is receiving from the California Institute for Regenerative Medicine The California Institute for Regenerative Medicine (CIRM) was created by California's Proposition 71 (2004), which authorized it to issue $3 billion in grants, funded by bonds, over ten years for embryonic stem cell and other biomedical research. will be an important element to succeeding in the fight against heart disease," Marban said. "What we work on in our stem cell lab today could translate into tomorrow's innovative treatment for heart attack patients." "We are delighted that Dr. Marban is receiving CIRM funding to continue his groundbreaking translational science devoted to regenerating diseased myocardial myocardial /myo·car·di·al/ (-kahr´de-al) pertaining to the muscular tissue of the heart. myocardial pertaining to the muscular tissue of the heart (the myocardium). tissue," said Shlomo Melmed, M.D., Cedars-Sinai Medical Center Cedars-Sinai Medical Center is a world-renowned hospital located in Los Angeles, California. History Cedars-Sinai is the result of a merger in 1961 between two major Los Angeles hospitals, Cedars of Lebanon and Mount Sinai Home for the Incurables, with Steve Broidy as vice president of academic affairs and dean of the medical faculty. "This award validates the leading role of the Cedars-Sinai Heart Institute in developing cutting-edge treatments for heart disease." Copyright : Euclid Infotech Pvt. Ltd. Provided by Syndigate.info an Albawaba.com company |
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