UPDATE: Thiazolidinedione Group.March 2000 This card replaces pages 15 and 16 of the booklet Medicines for People with Diabetes, covering all pills in the thiazolidinedione (THIGH-ah-ZO-li-deen-DYE-own) group. Thiazolidinedione pills make your cells more sensitive to insulin. The insulin can then move glucose from your blood into your cells for energy. Medicines in this group are for people with type 2 diabetes type 2 diabetes n. See diabetes mellitus. . Other names for this medicine Generic name Brand name pioglitazone Actos (py-oh-GLIT-uh-zone) (ACT-ose) rosiglitazone Avandia (rose-ee-GLIT-uh-zone) (uh-VAN-dee-uh) How often should I take pioglitazone or rosiglitazone? * Pioglitazone: Usually once a day. * Rosiglitazone: Either once or twice a day. When should I take pioglitazone or rosiglitazone? * Pioglitazone: At about the same time each day, with or without a meal. * Rosiglitazone: At about the same time each day, usually in the morning, with or without a meal. Or in the morning and in the evening, with or without meals. What are the possible side effects Side effects Effects of a proposed project on other parts of the firm. of pioglitazone or rosiglitazone? * If you take pioglitazone or rosiglitazone, it is important for your health care provider to check your liver enzyme levels regularly. Call your doctor right away if you have any signs of liver disease Liver Disease Definition Liver disease is a general term for any damage that reduces the functioning of the liver. Description The liver is a large, solid organ located in the upper right-hand side of the abdomen. : nausea, vomiting, stomach pain, lack of appetite, tiredness, yellowing of the skin or whites of the eyes, or dark-colored urine. (Some people who took troglitazone troglitazone a thiazolidinedione compound that enhances peripheral insulin resistance in the management of diabetes mellitus. , another thiazolidinedione, have had serious liver problems. Troglitazone is no longer available.) * Medicines in this group don't cause blood sugar to drop too low. But if you take other diabetes medicines along with medicines in this group, your blood sugar might drop too low. (See pages 27, 28, and 29 for information about low blood sugar.) * If you take birth control pills birth control pill n. See oral contraceptive. birth control pill Oral contraceptive, see there , medicines in this group might make your birth control pills less effective in preventing pregnancy. These medicines may increase your chances of getting pregnant. * You may gain weight while taking these medicines. * You may be at risk for developing anemia (uh-NEE-mee-ah), which will make you feel tired. Anemia causes your blood to carry less oxygen (OX-ih-jen) than normal. * You may have swelling in your legs or your ankles, also called edema edema (ĭdē`mə), abnormal accumulation of fluid in the body tissues or in the body cavities causing swelling or distention of the affected parts. (eh-DEE-mah). Are other diabetes medicines used with thiazolidinediones? Yes, your health care provider may ask you to take another diabetes medicine along with a thiazolidinedione. Or you may take a thiazolidinedione as your only diabetes medicine. These combinations work well together to control blood sugar: * Pioglitazone with a sulfonylurea sulfonylurea /sul·fo·nyl·urea/ (sul?fo-nil-u-re´ah) any of a class of compounds that exert hypoglycemic activity by stimulating the islet tissue to secrete insulin; used to control hyperglycemia in patients with type 2 diabetes mellitus (SUL-fah-nil-YOO-ree-ah), metformin metformin /met·for·min/ (met-for´min) an antihyperglycemic agent that potentiates the action of insulin, used in the treatment of type 2 diabetes mellitus. met·for·min n. (met-FOR-min), or insulin. * Rosiglitazone with metformin. National Diabetes Information Clearinghouse The National Diabetes Information Clearinghouse(NDIC) is an information dissemination service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The NIDDK is part of the National Institutes of Health, which is part of the U.S. 1 Information Way Bethesda, MD 20892-3560 Phone: (301) 654-3327 Fax: (301) 907-8906 Email: ndic@info.niddk.nih.gov This publication is not copyrighted. The clearinghouse encourages users of this card to duplicate and distribute as many copies as desired. This information is also available under "Health Information" at www.niddk.nih.gov on the Internet. |
|
||||||||||||||||||
Printer friendly
Cite/link
Email
Feedback
Reader Opinion