UMBILICAL CORD BLOOD HAILED AS IMMUNE SYSTEM RESTORATIVE.Byline: Richard Cole Associated Press Saving a few ounces of blood from a newborn's umbilical cord umbilical cord (ŭmbĭl`ĭkəl), cordlike structure about 22 in. (56 cm) long in the pregnant human female, extending from the abdominal wall of the fetus to the placenta. saves lives - that's the message going out to parents and obstetricians from a growing network of U.S. medical centers. The blood left in the baby's afterbirth afterbirth /af·ter·birth/ (af´ter-birth?) the placenta and membranes delivered from the uterus after childbirth. af·ter·birth n. contains the same immunity-producing stem cells stem cells, unspecialized human or animal cells that can produce mature specialized body cells and at the same time replicate themselves. Embryonic stem cells are derived from a blastocyst (the blastula typical of placental mammals; see embryo), which is very young found in bone marrow, and is far easier to transplant, researchers say. A half-dozen umbilical cord blood umbilical cord blood Transplantation A source of primitive and stem cells that can be used to reconstitute BM destroyed by aplastic anemia or by RT or chemotherapy for CA, lymphoproliferative malignancies. See Bone marrow transplantation, Stem cell therapy. banks have sprung up across the country or are in the planning stages. They already have given a new chance at life for victims of some forms of leukemia, anemia, Hodgkin's disease Hodgkin's disease, a type of cancer of the lymphatic system. First identified in 1832 in England by Thomas Hodgkin, it is a type of malignant lymphoma. Incidence peaks in young adults and the elderly. and other conditions. In February, 1-year-old Blayke LaRue of Oxnard, who suffered from a rare immune system immune system Cells, cell products, organs, and structures of the body involved in the detection and destruction of foreign invaders, such as bacteria, viruses, and cancer cells. Immunity is based on the system's ability to launch a defense against such invaders. disease, underwent a cord blood cord blood n. Blood present in the umbilical vessels at the time of delivery. transplant thanks to an anonymous donation, says his grateful father, Scott LaRue. ``He'll be perfectly normal,'' the father said. ``He'll have the immune system of that baby that donated that cord blood.'' LaRue urges all prospective parents to consider donating. ``Donate your cord,'' he urged. ``It's just going to be thrown away anyway. It doesn't cost any money. And it could save a life.'' Blayke received the transplanted blood from the San Mateo-based International Cord Blood Foundation, one of the biggest of the new banks. Foundation director Larry Andreini says 10,000 umbilical cords are discarded daily in the United States. The blood from those cords is superior to hard-to-match bone marrow when it comes to transplants, he says. ``It takes four months for a normal bone marrow search,'' he said. ``You can lose a child in four months. But a cord blood sample can be available in 48 hours.'' While bone marrow requires an almost exact match, cord blood transplants can be done without as close a fit, apparently because the stem cells are more primitive, or the brand-new donor has not yet developed antibodies that turn against the recipient. Withdrawing the less than three ounces of blood left in the umbilical cord is painless and quick. That compares to the time-consuming process of finding a bone marrow match, withdrawing it from a donor and then screening it for diseases. In St. Louis, the cord blood program organized by Dr. Donna Wall of Cardinal Glennon Children's Hospital SSM Cardinal Glennon Children's Hospital is a hospital in St. Louis, Missouri named after the Catholic Cardinal John J. Glennon in the St. Louis archdiocese. Cardinal Glennon hospital first opened in 1956 and continues to be operated by SSM, the Sisters of St. Mary. is called ``First Gift.'' Seventy-five obstetricians and 25 hospitals around St. Louis participate in First Gift, collecting cord blood after delivering babies. Wall says cord blood overcomes another limitation of bone marrow programs - the preponderance of European-ancestry donors, which makes it difficult for minorities to find matches. |
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