UK Biobank Validates Whatman FTA Elute for Long-Term Storage of Dried Blood Samples at Room Temperature.MANCHESTER, England -- Results from Intensive Trials of Newest Whatman DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. Storage Product Will Be Presented at Today's UK Biobank UK Biobank is a large long-term study in the United Kingdom (UK) which is investigating the respective contributions of genetic predisposition and environmental exposure (including nutrition, lifestyle, medications etc.) to the development of disease. It began in 2007. Conference, "Laboratory Aspects of Biobanking" Whatman plc., a global leader in separations technology, today announced that the UK Biobank, as part of an extensive scientific study aimed at validating their laboratory processes, has completed a series of experiments with several products, including Whatman FTA FTA abbr. Future Teachers of America Elute e·lute tr.v. e·lut·ed, e·lut·ing, e·lutes To extract (one material) from another, usually by means of a solvent. [From Latin , to validate their suitability for the long term archiving of dried blood samples. As they enter the final stages of refining their protocol for the collection and storage of biological samples, the UK Biobank has been pleased with the results achieved using FTA Elute. The organization will present their full findings and conclusions at today's conference, "Laboratory Aspects of Biobanking." "By storing dried blood, we will achieve significant savings in terms of both cost and storage space," said Dr. Tim Peakman, Executive Director of the UK Biobank. "But the savings would have been irrelevant if we did not have confidence in the long-term integrity of our samples. For example, by providing for room temperature storage, FTA and FTA Elute eliminate the freeze/thaw sample degradation of stored cellular fractions inherent in traditional ultra low temperature storage approaches." "A broad network of academic collaborators, who have used a wide variety of matrices, steered us toward Whatman FTA and FTA Elute," added Dr. Peakman. "Both products proved their ability to provide stable and cost-effective storage of samples, but FTA Elute seems more conducive to the purposes of the UK Biobank. Through a simple heat and water elution elution /elu·tion/ (e-loo´shun) in chemistry, separation of material by washing; the process of pulverizing substances and mixing them with water in order to separate the heavier constituents, which settle out in solution, from the step, FTA Elute releases the DNA, reducing contamination from the matrix and allowing us to perform fewer PCR PCR polymerase chain reaction. PCR abbr. polymerase chain reaction Polymerase chain reaction (PCR) amplification cycles to reach a saturation endpoint." FTA Elute, the newest extension of the Whatman FTA product line, binds proteins, hemoglobin and other PCR inhibitors to create an extremely stable environment that allows DNA to be stored at room temperature. The unique benefit of FTA Elute is its ability to ultimately release the stored DNA into liquid, the ideal scenario for organizations that need to perform multiple amplification reactions from a single DNA sample. About The UK Biobank Founded in 2003, the UK Biobank is a long-term national project dedicated to building the world's largest information resource for medical researchers. By following the health of 500,000 volunteers aged 40-69 in the UK for up to 20 years, the Years, The the seven decades of Eleanor Pargiter’s life. [Br. Lit.: Benét, 1109] See : Time project is intended to help approved researchers develop new and better ways of preventing, diagnosing and treating common illnesses such as cancer, heart disease, diabetes and Alzheimer's disease Alzheimer's disease (ăls`hī'mərz, ôls–), degenerative disease of nerve cells in the cerebral cortex that leads to atrophy of the brain and senile dementia. . About Whatman Whatman is a global leader in separations technology and is known in the scientific community for providing innovative life science products and solutions. With the acquisition of Schleicher & Schuell, Whatman offers a more comprehensive product range to its customers worldwide and enters the proteomics market with Schleicher & Schuell's core competency A core competency is something that a firm can do well and that meets the following three conditions specified by Hamel and Prahalad (1990):
FTA(R) and FTA(R) Elute are registered trademarks of the Whatman Group. |
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