Transforming growth factor-[beta] in cancer therapy; v.2: Cancer treatment and therapy.9781588297150 Transforming growth factor- transforming growth factor–β1, –β2 Molecular biology Factors responsible for positive and negative autocrine growth regulation [beta] in cancer therapy; v.2: Cancer treatment and therapy. Ed. by Sonia B. Jakowlew. Humana Press Inc. 2008 786 pages $169.00 Hardcover Cancer drug discovery and development QP552 Jakowlew, of the National Cancer Institute in Bethesda, is the editor of this two-volume collection of articles (the volumes are sold individually), with basic and clinical biology in Vol.1 and articles on cancer treatment and therapy in Vol.2. This volume is divided into three parts, with the first part consisting of 17 chapters on transforming growth factor [Beta], or TGF TGF transforming growth factor. [Beta], in developing and advanced cancers, with chapter topics that include the role of TGF[Beta] in osteolytic osteolytic adjective Causing bone breakdown bone metastases bone metastases Oncology Cancer that has spread from a primary tumor to the bone , TGF[Beta] and progression of esophageal cancer Esophageal Cancer Definition Esophageal cancer is a malignancy that develops in tissues of the hollow, muscular canal (esophagus) along which food and liquid travel from the throat to the stomach. , and key roles of TGF[Beta] and Smad3 in prostate cancer. Part Two contains 16 chapters on TGF[Beta] in cancer treatment and therapy and Part Three presents 11 chapters on developing inhibitors of TGF[Beta] signaling for therapy. The authors, who are with medical research institutions worldwide, discuss their own research and provide both introductory abstracts and full lists of references in each chapter. Both volumes constitute a significant addition to the field. ([c]20082005 Book News, Inc., Portland, OR) |
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