Tokyo Institute of Technology Identifies Molecular Switch in Gene Expression.Tokyo, Japan, Jan 20, 2006 - (JCN JCN Japan Corporate News JCN Journal of Cognitive Neuroscience JCN Journal of Cardiovascular Nursing JCN Journal of Christian Nursing JCN Job Control Number JCN Journal of Child Neurology JCN joint communications network (US DoD) ) - The Tokyo Institute of Technology Tokyo Institute of Technology (東京工業大学 announced on January 20 that Professor Hiroshi Handa's research group of its Graduate School of Bioscience and Biotechnology has identified a molecular switch in gene expression. The research group has confirmed that P-TEFb, a kind of phosphorylated enzyme, can switch the activity of DSIF DSIF Dirty South Improv Festival DSIF Deep Space Instrumentation Facility DSIF Defensive Systems Integration Facility DSIF Distinguished Space Industry Fellows Program , a protein that regulates the transcription elongation of genes. Specifically, P-TEFb phosphorylates DSIF so that DSIF can switch on and off the process of gene expression. Details of the research are available in the January 20 issue of Molecular Cell, a US science magazine, under the title of "P-TEFb-mediated phosphorylation phosphorylation, chemical process in which a phosphate group is added to an organic molecule. In living cells phosphorylation is associated with respiration, which takes place in the cell's mitochondria, and photosynthesis, which takes place in the chloroplasts. of hSpt5 C-terminal repeats is critical for processive transcription elongation". Copyright [c] 2006 Japan Corporate News Network. All rights reserved. |
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