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Title: Potential for Early Disease Detection Promotes European Personalised Medicine and Pharmacogenomics Market Growth.


DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c65095) has announced the addition of the new Frost & Sullivan "European Personalised Medicine and Pharmacogenomics Pharmacogenomics is the branch of pharmacology which deals with the influence of genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with a drug's efficacy or toxicity.  Markets" to their offering.

The Frost & Sullivan research service titled European Personalised Medicine and Pharmacogenomics Market provides an overview of the pharmacogenomic tests, together with the revenues, key market drivers, restraints, and trends in the market. This apart, it provides strategic solutions to the vendors to gain advantage in this growing market, and also discusses the available pharmacogenomics options in detail for other areas to determine a clinical course of therapeutic treatments; for example, cardio-vascular disease, stroke and type II diabetes Type II diabetes
Type II diabetes is the most common form of diabetes and usually appears in middle aged adults. It is often associated with obesity and may be delayed or controlled with diet and exercise.

Mentioned in: Diabetic Ketoacidosis
.

Potential for Early Disease Detection Promoting Market Growth

The ability to detect a disease in its very early stage and the subsequent advantages of better clinical outcomes are proving major drivers for the growing adoption of pharmacogenomic tests across Europe. Pharmacogenomics can be used to detect a predisposition predisposition /pre·dis·po·si·tion/ (-dis-po-zish´un) a latent susceptibility to disease that may be activated under certain conditions.

pre·dis·po·si·tion
n.
1.
 toward a particular disease and for growing disease markets such as cardiovascular diseases Cardiovascular disease
Disease that affects the heart and blood vessels.

Mentioned in: Lipoproteins Test

cardiovascular disease 
, diabetes and cancer, a genetics-based test could identify patients for long-term prophylactic prophylactic /pro·phy·lac·tic/ (pro?-fi-lak´tik)
1. tending to ward off disease; pertaining to prophylaxis.

2. an agent that tends to ward off disease.


pro·phy·lac·tic
n.
 therapy. This, in turn will decrease the use of expensive therapies and invasive procedures, in addition to reducing bed occupancy and lessening the burden on the healthcare system. Considering these advantages, governments across Europe have initiated campaigns to encourage the population to be screened on certain types of diseases such as cancer, which have significantly helped better patient management.

Despite all this, inherent problems regarding the time and cost associated with the development of diagnostic tests remain major restraints for market growth. Moreover, obtaining intellectual property for pharmacogenomic tests pose significant challenges for companies. "As companies identify novel compounds, a strong intellectual property system is necessary to stimulate investment in innovation," notes the analyst of this research service." It is essential that the European Governments' patent systems offer protection for innovations relating to relating to relate prepconcernant

relating to relate prepbezüglich +gen, mit Bezug auf +acc 
 personalised medicine, as well as high quality patent examination that allows patents of appropriate scope and quality."

Hybridisation Techniques Remain Dominant

With regard to technology, hybridisation techniques tend to be the major technologies utilised in the field of pharmacogenomics, and fluorescence in-situ hybridisation (FISH) continues to be widely used due to its ability to detect a variety of chromosomal and genetic aberrations such as molecular translocation translocation /trans·lo·ca·tion/ (trans?lo-ka´shun) the attachment of a fragment of one chromosome to a nonhomologous chromosome. Abbreviated t.  deletions specific to each entity of haematological Adj. 1. haematological - of or relating to or involved in hematology
hematologic, hematological
 malignancies in a single non-dividing interphase interphase /in·ter·phase/ (in´ter-faz) the interval between two successive cell divisions, during which the chromosomes are not individually distinguishable.

in·ter·phase
n.
 cell. The HER-2/neu gene is a prime example of a successful pharmacogenomic test that has both diagnostic and prognostic prog·nos·tic
adj.
1. Of, relating to, or useful in prognosis.

2. Of or relating to prediction; predictive.

n.
1. A sign or symptom indicating the future course of a disease.

2.
 value. Abbott Diagnostics' (Vysis) PathVysion is a FISH-based test that has an addition of Genetech's Herceptin for patients who may require treatment. The technology is capable of diagnosing multiple gene copies characteristic of HER-2/neu over expression in breast cancer. Developments in the microarray and genotype genotype (jēn`ətīp'): see genetics.
genotype

Genetic makeup of an organism. The genotype determines the hereditary potentials and limitations of an individual.
 assay technologies are also expected to aid the growth of the pharmacogenomics during the next few years.

"Among the regional markets, the German pharmacogenomics market was the largest revenue generator in 2005, primarily due to the high level of awareness about pharmacogenomics among medical professionals as well as the public," says the analyst. "Following the German market was France, which has radically changed the emphasis on disease management uniformity, focussing more on individual patient management, as the technology of personalised medicine has become inexpensive and more readily available."

For more information, visit http://www.researchandmarkets.com/reports/c65095
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Publication:Business Wire
Date:Aug 8, 2007
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