Tinnitus Research.For the first time, scientists have located an area in the brain involved in the production of tinnitus Tinnitus Definition
Tinnitus is hearing ringing, buzzing, or other sounds without an external cause. Patients may experience tinnitus in one or both ears or in the head. . Tinnitus is a ringing, roaring, buzzing, or clicking sound that occurs inside the head. These findings are in a new study by Alan H. Lockwood, M.D., of the State University of New York (body) State University of New York - (SUNY) The public university system of New York State, USA, with campuses throughout the state. in Buffalo and his colleagues, in the January 22, 1998, issue of Neurology.
Using positron-emission tomography (PET), Dr. Lockwood's group was able to map brain regions of individuals who had tinnitus in only one ear. These individuals also had the ability to change the loudness of their tinnitus by performing special movements of their face and mouth. Cerebral blood flow Cerebral blood flow, or CBF, is the blood supply to the brain in a given time. In an adult, CBF is 750 mls/min or 15% of the cardiac output. On a weight basis, this is 50 to 54 milllitres/100grams/minute. , an indication of increased brain activity, was measured while these individuals were at rest, and performed the movements that affected their tinnitus, and while listening to loud beeps or pure tones that were presented using ear phones. The PET scan PET scan (pĕt) or positron emission tomography (pŏz`ĭtrŏn' ĭmĭsh`ən təmŏg`rəfē) detected changes in the auditory cortex auditory cortex
The region of the cerebral cortex that receives auditory data from the medial geniculate body. Also called auditory area. , that part of the brain that processes sounds, on the side of the brain opposite the tinnitus. In contrast, the auditory cortex on both sides of the brain reacted to pure tones presented to one ear at a time. Since external tones presented to one ear affect both sides of the brain, the fact that the internal tones of tinnitus affect only one side of brain indicate that tinnitus may be initiated by brain activity rather than by the ear.
"This work represents a breakthrough and moves us a step closer to understanding the phenomenon of tinnitus. We feel certain that this study will lead to further research that will ultimately translate into treatment options for the millions of people who suffer with this difficult condition," said James F. Battey, M.D., Ph.D., Director, National Institute on Deafness and Other Communication Disorders The National Institute on Deafness and Other Communication Disorders (NIDCD), a member of the U.S. National Institutes of Health, is mandated to conduct and support biomedical and behavioral research and research training in the normal and disordered processes of hearing, balance, (NIDCD NIDCD National Institute on Deafness & other Communication Disorders ), which funded the study.
The authors suggest that this study may improve knowledge of how tinnitus occurs and may lead to finding treatments. "Without objective information on how and where the condition originates, developing effective treatments has been difficult. We have taken a critical step down the road toward a cure for this disabling condition," said Lockwood. Ultimately, this study opens the door to further research such as the development of drugs to change the brain activity in the involved areas. Dr. Lockwood's colleagues are R.J. Salvi, Ph.D., M.L. Coad, B.A., M.L. Towsley, M.A., D.S D.S Drainage Structure (flood protection) . Wack, M.A., and B.W. Murphy, M.S., from the VA Western New York
Western New York refers to the westernmost region of New York State. Health Care System and State University of New York, both in Buffalo.
Tinnitus is a symptom that accompanies many kinds of hearing loss. The phenomenon of tinnitus presents so many issues to address because there are many different experiences of tinnitus with many different causes. The mechanisms that produce tinnitus are not fully known and are associated with nearly all diseases and disorders of the ear that cause hearing loss. Controlling these mechanisms, therefore, may alleviate the tinnitus. As it is a symptom, tinnitus is difficult for the scientists to address. The NIDCD is supporting several biomedical research Biomedical research (or experimental medicine), in general simply known as medical research, is the basic research or applied research conducted to aid the body of knowledge in the field of medicine. projects that cover a variety of aspects of the condition which will provide necessary data: developing a comprehensive database and an understanding of the phenomenon of tinnitus that accompanies sensorineural hearing loss Sensorineural hearing loss
Hearing loss caused by damage to the nerves or parts of the inner ear governing the sense of hearing.
Mentioned in: Tinnitus
sensorineural hearing loss ; tinnitus and masking devices; the role of calcium imbalance in inducing cochlear cochlear
pertaining to or emanating from the cochlea.
the coiled portion of the membranous labyrinth located inside the cochlea; contains endolymph.
see Table 14. tinnitus; and otoacoustic emissions and cochlear function. The NIDCD is also supporting several non-invasive imaging studies that will hopefully differentiate the various kinds of tinnitus.
As the nation's focal point focal point
See focus. for research in human communication, the NIDCD conducts and supports biomedical bi·o·med·i·cal
1. Of or relating to biomedicine.
2. Of, relating to, or involving biological, medical, and physical sciences. and behavioral research and research training on normal mechanisms as well as diseases and disorders of hearing, balance, smell, taste, voice, speech and language that affect 46 million Americans. The NIDCD is one of the institutes of the National Institutes of Health, the Nation's lead agency for biomedical and behavioral health research. More information on NIDCD research, programs, and activities can be found on the NIDCD web site at www.nih.gov/nidcd/.
Additional Information Resources:
NIDCD Information Clearinghouse Address: 1 Communication Avenue Bethesda, MD 20892-3456 Voice: 1-800-241-1044 TTY: 1-800-241-1055 E-mail: firstname.lastname@example.org American Tinnitus Association (ATA) Address: P.O. Box 5 Portland, OR 97207 Voice: (503) 248-9985 8:30 a.m. - 5 p.m., Pacific time Toll Free: (800) 634-8978 FAX: (503) 248-0024 Internet: http://www.teleport.com/~ata American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) Address: One Prince Street Alexandria, VA 22314 Voice: (703) 519-1589 TTY: (703) 519-1585 FAX: (703) 519-1587 E-mail: email@example.com Internet: http://www.entnet.org Self Help for Hard of Hearing People, Inc. (SHHH) Address: 7910 Woodmont Avenue Suite 1200 Bethesda, MD 20814 Voice: (301) 657-2248 TTY: (301) 657-2249 FAX: (301) 913-9413 Internet: http:/www.shhh.org/ American Academy of Audiology (AAA) Address: 8201 Greensboro Drive Suite 300 McLean, VA 22102 Voice/TTY: (703) 610-9022 8 a.m. -5 p.m., eastern time Toll Free: (800) AAA-2336 Internet: http://www.audiology.org American Speech-Language-Hearing Association (ASHA) Address: 10801 Rockville Pike Rockville, MD 20852 Voice/TTY: (301) 897-5700 Toll Free: (800) 638-8255 8:30 a.m. - 5 p.m., eastern time FAX: (301) 571-0457 Internet: http://www.asha.org/