Tienta Sciences Announces First Sale of SpectRIM.

INDIANAPOLIS -- Proteomics start-up company Tienta Sciences, Inc. has announced the first sale of its premier product SpectRIM(TM), a substrate that allows Raman and Infrared (IR) spectroscopy and MALDI mass spectrometry of protein specimens. The company's sale of SpectRIM substrate kits is to Jobin Yvon-Horiba, a leading manufacturer of analytical Raman, reflectance IR spectroscopy, and mass spectrometry as well as reflectance light microscopy on the same sample.

David Kolasinski, Tienta Sciences Vice President of Sales and Marketing, said, "This is a major milestone for Tienta Sciences. We are pleased to initiate our entry into the market with Jobin Yvon-Horiba's selection of SpectRIM. Jobin Yvon-Horiba is the market leader in micro-Raman Spectroscopy."

Andrew Whitley, Ph.D., Director, Raman Spectroscopy Group, Jobin Yvon said, "The SpectRIM substrates offer Femtomole sensitivity, ideal for protein arrays, HPLC and any low concentration solution studies. It provides the researcher with Information not available today."

Raman Spectroscopy

Raman spectroscopy involves the inelastic scattering of light, providing more detailed information with higher sensitivity using smaller samples, without sample preparation or destruction during testing. Tienta's SpectRIM substrate represents a key advancement in the new era of protein discovery and characterization.

Raman processes have the potential to rapidly accelerate the discovery and characterization of high-value biotherapeutics and to monitor their production. Raman spectroscopy has major applications in drug discovery, food testing, nutraceutical monitoring, and the forensics, environmental and chemical industries.

SpectRIM(TM)

SpectRIM(TM) is a Hydrophobic Stainless Steel Substrate for Raman and Reflectance IR Spectroscopy. The highly reflective surface has almost no detectable Raman or IR background signal. This substrate is ideal for measuring small quantities of material, especially from dilute aqueous solutions. Tienta's substrate increases Raman sensitivity allowing the use of femtomole amounts of protein to measure structural changes or modifications that cannot be detected in other ways.

--Tienta's proprietary substrate allows the researcher to gather information on the same sample, from Raman, Infrared and Mass Spectroscopy.

--Improved sensitivity allows for the detection of protein-protein, protein-antigen, conformational and structural changes, post translational modifications such as phosphorylation and glycosylation non-destructively without the need for external labeling of the molecule.

About Tienta Sciences

Tienta Sciences is headquartered in the Indiana State Certified Technology Park at the Indiana University Emerging Technologies Center in Indianapolis. With laboratories in the Purdue Research Park in West Lafayette, Indiana, Tienta Sciences develops products to facilitate Raman, infrared and mass-spectroscopy analysis to monitor and assess changes in proteins in a manner that provides greater sensitivity and significant cost savings over current technology. Tienta Sciences is a spin-off company of Inproteo LLC, a company established by Eli Lilly and Company, Indiana University and Purdue University to commercialize cutting-edge research in proteomic tools and analytical methods.

Tienta Sciences is currently seeking additional capital and is poised to announce further products for the biotechnology and pharmaceutical industries. For more information, visit http://www.tientasciences.com or contact David Kolasinski, Tienta Sciences Vice President of Sales and Marketing, phone [phone] or email [e-mail].