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There Are Currently No Less Than 220 Emerging Therapeutics Targeting Prostate Cancer, from Early Preclinical to Marketed Drugs.


DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c48450) has announced the addition of the new Bioseeker report "Prostate Cancer prostate cancer, cancer originating in the prostate gland. Prostate cancer is the leading malignancy in men in the United States and is second only to lung cancer as a cause of cancer death in men. : Drug Pipeline Update 2007" to their offering.

Cancer of the prostate is the second most frequently diagnosed cancer in men in the US. Several new approvals have changed the panorama for options in the treatment of late stage prostate cancer. Abarelix was approved in November 2003 for the palliative treatment of men with advanced symptomatic prostate cancer. In May 2004 docetaxel was approved for use in combination with prednisone prednisone (prĕd`nĭsōn): see corticosteroid drug.  as a treatment for patients with androgen independent (hormone refractory) metastatic Metastatic
The term used to describe a secondary cancer, or one that has spread from one area of the body to another.

Mentioned in: Coagulation Disorders


metastatic

pertaining to or of the nature of a metastasis.
 prostate cancer. Additionally, in October 2004 FDA FDA
abbr.
Food and Drug Administration


FDA,
n.pr See Food and Drug Administration.

FDA,
n.pr the abbreviation for the Food and Drug Administration.
 approved histrelin for the palliative treatment of advanced prostate cancer. Finally, leuprolide was approved by FDA in January 2002 for the palliative treatment of advanced prostate cancer. One example of market penetration in this field is that analysts forecasts Abarelix a sales of $450 million in 2006.

There are today no less than 220 emerging therapeutics targeting prostate cancer, from early preclinical to marketed drugs. Prostate Cancer Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Read more below how Prostate Cancer Drug Pipeline Update is organized:

Investigators Includes more than 160 investigators plus their collaborators

Drug name & Synonyms Lists commercial, generic and code names for drugs. In several hundreds of synonym names

Developmental stage contains more than 220 drugs in active development included in:

* 20 marketed drugs

* 10 projects in Phase III

* 100 projects in Phase II

* 40 projects in Phase I

* 50 projects in Preclinical

Mechanism/Target Includes mechanisms of action:

* Apoptosis agonists

* DNA DNA: see nucleic acid.
DNA
 or deoxyribonucleic acid

One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes.
 antagonists

* DNA topoisomerase ATP ATP: see adenosine triphosphate.
ATP
 in full adenosine triphosphate

Organic compound, substrate in many enzyme-catalyzed reactions (see catalysis) in the cells of animals, plants, and microorganisms.
 hydrolysing inhibitors

* Microtubule microtubule

Tubular structure enclosed by a membrane found within animal and plant cells. Of varying length, they have several functions. They help give shape to many cells and are major components of cilia and flagella, participate in the formation of the spindle during
 inhibitors

* Immunostimulants

* Ribonucleoside ribonucleoside /ri·bo·nu·cleo·side/ (-noo´kle-o-sid) a nucleoside in which the purine or pyrimidine base is combined with ribose.

ri·bo·nu·cle·o·side
n.
 diphosphate di·phos·phate
n.
An ester of phosphoric acid containing two phosphate groups.
 reductase reductase /re·duc·tase/ (-tas) a term used in the names of some of the oxidoreductases, usually specifically those catalyzing reactions important solely for reduction of a metabolite.  inhibitors

* Protein kinase inhibitors

* CD molecule antagonists

Etc.

Compound Lists compound name or type of compound:

* Antibodies

* Chemical names

* Enzymes

* Nucleotides

* Peptides

* Proteins

* Ribozymes

Etc.

Description Progress analysis and review of drug development.

A typical drug profile reports on:

* Drug Name & Synonyms

* Investigator(s)

* Indication(s)

* Developmental Stage(s)

* Mechanism(s)

* Target(s)

* Clinical Development

* Developmental History

* Scientific Data

* Patents

* In/Out-licensing

* Collaborations

* Analysts Comments

How May Drug Pipeline Update Be of Use?

* Show investors/board/management that you are right on top of drug development progress in your therapeutic area.

* Find competitors, collaborations partners, M&A candidates etc.

* Jump start competitive drug intelligence operations

* Excellent starting point for world wide benchmarking

* Compare portfolio and therapy focus with your peers

* Speed up pro-active in-/outlicensing strategy work

* Fast and easy way of tracking drugs using search engines; just one click and you may search World Wide Web and PubMed for any drug with all its synonyms.

Drug Pipeline Update is fitted into a CD-ROM CD-ROM: see compact disc.
CD-ROM
 in full compact disc read-only memory

Type of computer storage medium that is read optically (e.g., by a laser).
 based application, for your intelligent usage:

* Smart CD-ROM application, which makes it easy to use and navigate by

* Multiple search and sort functions included

* Drug data is linked to search engines like Google and PubMed

* Direct links to web pages from inside the application

* Found information is easily shared with others over email, file export or in print

For more information visit http://www.researchandmarkets.com/reports/c48450.
COPYRIGHT 2007 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2007, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Jan 15, 2007
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