The Largest Expansion in the Proteomic Technologies Market Will Be in Bioinformatics and Protein Biochip Technologies.DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c1715) has announced the addition of Jain PharmaBiotech's "Proteomics - Technologies, Markets and Companies" to their offering. This report describes and evaluates the proteomic technologies that will play an important role in drug discovery, molecular diagnostics and practice of medicine in the post-genomic era - the first decade of the 21st century. Most commonly used technologies are 2-D gel electrophoresis gel electrophoresis n. Electrophoresis performed in a gel composed of agarose, polyacrylamide, or starch. for protein separation and analysis of proteins by mass spectrometry mass spectrometry or mass spectroscopy Analytic technique by which chemical substances are identified by sorting gaseous ions by mass using electric and magnetic fields. . Microanalytical protein characterization with multidimentional liquid chromatography/mass spectrometry spectrometry /spec·trom·e·try/ (spek-trom´e-tre) determination of the wavelengths or frequencies of the lines in a spectrum. spec·trom·e·try n. improves the throughput and reliability of peptide mapping. Matrix-Assisted Laser Desorption Desorption A process in which atomic and molecular species residing on the surface of a solid leave the surface and enter the surrounding gas or vacuum. Mass Spectrometry (MALDI-MS MALDI-MS Matrix assisted Laser Desorption Ionisation Mass Spectrometry ) has become a widely used method for determination of biomolecules This page aims to list articles on Wikipedia that describe particular biomolecules or types of biomolecules. This list is not necessarily complete or up to date - if you see an article that should be here but isn't (or one that shouldn't be here but is), please update the page including peptides, proteins. Functional proteomics technologies include yeast two-hybrid system for studying protein- protein interactions. Establishing a proteomics platform in the industrial setting initially requires implementation of a series of robotic systems robotic system An integrated system of devices that automate production and manufacturing of goods and services Surgery An AI-based surgical assistant system, which processes sensory input from haptic interfaces and/or allows surgeons to act with more accuracy than to allow a high-throughput approach for analysis and identification of differences observed on 2-D electrophoresis electrophoresis (ĭlĕk'trōfərē`sĭs): see colloid. electrophoresis Movement of electrically charged particles in a fluid under the influence of an electric field. gels. Protein chips are also proving to be useful. Proteomic technologies are now being integrated into the drug discovery process as complimentary to genomic approaches. Toxicoproteomics, i.e. the evaluation of protein expression for understanding of toxic events, is an important application of proteomics in preclincial drug safety. Use of bioinformatics is essential for analyzing the massive amount of data generated from both genomics and proteomics. Proteomics is providing a better understanding of pathomechanisms of human diseases. Analysis of different levels of gene expression in healthy and diseased tissues by proteomic approaches is as important as the detection of mutations and polymorphisms at the genomic level and may be of more value in designing a rational therapy. Protein distribution / characterization in body tissues and fluids, in health as well as in disease, is the basis of the use of proteomic technologies for molecular diagnostics. Proteomics will play an important role in medicine of the future which will be personalized and will combine diagnostics with therapeutics. The text is supplemented with 39 tables, 25 figures and over 400 selected references from the literature. The number of companies involved in proteomics has increased remarkably during the past few years. More than 300 companies have been identified to be involved in proteomics and 210 of these are profiled in the report with 437 collaborations. The markets for proteomic technologies are difficult to estimate as they are not distinct but overlap with those of genomics, gene expression, high throughput screening, drug discovery and molecular diagnostics. Collectively, the value of markets for proteomic technologies in the year 2005 was approximately $6 billion and is expected to increase to $10 billion by the year 2010 and $18 billion by the year 2015. The largest expansion will be in bioinformatics and protein biochip biochip Small-scale device, analogous to an integrated circuit, constructed of or used to analyze organic molecules associated with living organisms. One type of theoretical biochip is a small device constructed of large organic molecules, such as proteins, and capable of technologies. Important areas of application are cancer and neurological disorders This is a list of major and frequently observed neurological disorders (e.g. Alzheimer's disease), symptoms (e.g.back pain), signs (e.g. aphasia) and syndromes (e.g. Aicardi syndrome). Key topics covered include: --Basics of Proteomics --Proteomic Technologies --Protein biochip technology --Bioinformatics in Relation to Proteomics --Research and Pharmaceutical Applications of Proteomic Technologies --Application of Proteomics in Human Medicine --Commercial Aspects of Proteomics --Future of Proteomics For more information visit http://www.researchandmarkets.com/reports/c14198 Source: Jain PharmaBiotech |
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