The BioSciences Group of Fujitsu Announces BioMedCAChe(TM) and ActiveSite(TM) Licensing Agreement with Ensemble Discovery.Global leader in solutions for experimental scientists provides desktop molecular modeling platform to Cambridge-based novel chemical discovery company.WESTWOOD, Mass. and CAMBRIDGE Mass., Oct. 17 /PRNewswire/ -- The BioSciences Group of Fujitsu Computer Systems today announced a licensing agreement with Ensemble Discovery, a pioneer in synthetic chemistry research, for its BioMedCAChe(TM) suite of automated docking and molecular modeling software. The license will also provide Ensemble with the BioSciences Group's ActiveSite(TM) module for designing effective small molecule inhibitors of protein targets. "We are glad to provide Ensemble Discovery with the BioMedCAChe automated docking technology," said Dr. Michael J. McManus, Vice President of Business Development for the BioSciences Group. "The goal of the BioSciences Group is to supply innovative companies with powerful modeling tools that can match their workflow challenges and research objectives." Dr. Arturo J. Morales, Director of Informatics of Ensemble Discovery, said, "At Ensemble, we have a need to conduct sophisticated modeling of both small molecules and nucleic acids in order to better understand and predict the local forces acting on unimolecular reactions. BioMedCAChe brings this capability to the bench scientists directly." The Fujitsu BioMedCAChe suite provides powerful tools to speed the drug discovery process by enabling scientists to predict and select better quality leads. Analysis capabilities ranging from molecular mechanics The term molecular mechanics refers to the use of Newtonian mechanics to model molecular systems. The potential energy of all systems in molecular mechanics is calculated using force fields. to quantum mechanics quantum mechanics: see quantum theory. quantum mechanics Branch of mathematical physics that deals with atomic and subatomic systems. It is concerned with phenomena that are so small-scale that they cannot be described in classical terms, and it is and ab initio approaches are enabled on small molecules, polymers and macromolecules Macromolecules A large molecule composed of thousands of atoms. Mentioned in: Gene Therapy macromolecules including proteins and DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. . Scientists can view, analyze and modify structures using interactive sequence and 3D structure editor windows, as well as optimize macromolecules with tens of thousands of atoms, all on their desktop computers. The BioMedCAChe software also deals with protein-ligand interactions through graphical and analytical models. The ActiveSite option with FastDock(TM) automated docking enables scientists to dock rigid or flexible ligands into a protein with rigid or flexible sidechains. The ActiveSite module is superior to many competing docking packages that are constrained by molecular size and display speed, which require the use of expensive UNIX UNIX Operating system for digital computers, developed by Ken Thompson of Bell Laboratories in 1969. It was initially designed for a single user (the name was a pun on the earlier operating system Multics). workstations. BioMedCAChe software is currently the only desktop solution to offer such flexibility in configuration. About The BioSciences Group of Fujitsu Computer Systems The BioSciences Group of Fujitsu Computer Systems Corporation is an established leader in creating innovative and reliable solutions for experimental scientists. BioSciences Group solutions enable researchers to make in silico predictions about leads, targets, and interactions, and to validate these hypotheses experimentally. BioSciences Group offerings include the CELLINJECTOR(TM) system for high-throughput, automated cellular injection, the isS(TM) (in silico Screening) platform for large-scale docking and free energy of binding simulations, and the CAChe(TM) suite of life sciences predictive modeling and automated docking tools, for drug discovery lead- generation. For more information, please see: us.fujitsu.com/biosciences. About Fujitsu Computer Systems Headquartered in Sunnyvale, Calif., Fujitsu Computer Systems is a wholly owned subsidiary Wholly Owned Subsidiary A subsidiary whose parent company owns 100% of its common stock. Notes: In other words, the parent company owns the company outright and there are no minority owners. of Fujitsu Limited committed to the design, development and delivery of advanced computer systems and managed services for the business enterprise. The company offers a complete line of high- performance mobile computers, scalable and reliable servers, storage, and middleware as well as managed and professional services (job) professional services - A department of a supplier providing consultancy and programming manpower for the supplier's products. . Fujitsu Computer Systems emphasizes leading-edge technology, exceptional product quality and user comfort and productivity, as well as outstanding customer service. More information on Fujitsu Computer Systems is available at: us.fujitsu.com/computers. About Fujitsu Fujitsu is a leading provider of customer-focused IT and communications solutions for the global marketplace. Pace-setting device technologies, highly reliable computing and communications products, and a worldwide corps of systems and services experts uniquely position Fujitsu to deliver comprehensive solutions that open up infinite possibilities for its customers' success. Headquartered in Tokyo, Fujitsu Limited reported consolidated revenues of 4.7 trillion yen (US$44.5 billion) for the fiscal year ended March 31, 2005. For more information, please see: http://www.fujitsu.com/. About Ensemble Discovery Corporation Located in Cambridge, MA, Ensemble Discovery Corporation is an early stage company that is transforming the way scientists discover novel chemicals. Based on the groundbreaking work of Professor David Liu David Liu is a Taiwanese figure skater. He represented Taiwan at three Olympic Games: the 1998 Winter Olympics, where he placed 27th; 1992 Winter Olympics where he placed 17th; and the 1988 Winter Olympics, where he placed and 25th. of Harvard University Harvard University, mainly at Cambridge, Mass., including Harvard College, the oldest American college. Harvard College Harvard College, originally for men, was founded in 1636 with a grant from the General Court of the Massachusetts Bay Colony. , DNA Programmed Chemistry (DPC DPC Department of Premier and Cabinet (Victoria, Australia) DPC Dutch Power Cows DPC Deferred Procedure Calls (Microsoft Windows NT 4. (TM)) utilizes a specially designed genetic code to control chemical reactivity and guide the assembly of chemical structures. Ensemble has integrated DPC(TM) into a unique selection system that combines chemistry, biology and informatics to discover novel compounds. Ensemble utilizes DPC(TM) to generate new products that address significant unmet needs in therapeutics, detection and other specialty chemical markets. NOTE: Fujitsu, BioMedCAChe, ActiveSite, CELLINJECTOR, isS, FastDock and CAChe are trademarks or registered trademarks of Fujitsu Limited in the United States and other countries. DPC is a trademark of Ensemble Discovery Corporation in the United States and other countries. All other trademarks and product names are the property of their respective owners. CONTACT: Joshua Nathan of BioSciences Group of Fujitsu Computer Systems, +1-781-326-6330, or fax, +1-781-326-7179, jnathan@us.fujitsu.com; or Mario Fante of Aviator PR, +1-617-763-9887, or mario@aviator-pr.com, for BioSciences Group of Fujitsu Computer Systems Web site: http://www.fai.fujitsu.com/ |
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