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Talecris Provides Educational Grant to Support World Federation of Hemophilia's Global Laboratory Science Program.


Program Aims to Advance Patient Care Through Improved Diagnosis

RESEARCH TRIANGLE PARK Research Triangle Park, research, business, medical, and educational complex situated in central North Carolina. It has an area of 6,900 acres (2,795 hectares) and is 8 × 2 mi (13 × 3 km) in size. Named for the triangle formed by Duke Univ. , N.C. & MONTREAL -- Talecris Biotherapeutics, Inc. (http://www.talecris.com) and the World Federation of Hemophilia (WFH WFH World Federation of Hemophilia (Fédération Mondiale de l'Hémophilie)
WFH Working From Home
WFH Willem Frederik Hermans (Dutch writer)
WFH Work for Hire
WFH World Federation of Healing
) (http://www.wfh.org) jointly announced today that Talecris has provided WFH an educational grant to support its global Laboratory Science Program. The grant, totaling $160,000, provides funding for several program components that collectively seek to improve a laboratory's proficiency and expertise in the accurate and timely diagnosis of hemophilia, with an emphasis on developing countries. Additionally, a portion of the grant will be applied by WFH to its Corporate Partnership program, providing unrestricted funds in support of WFH's mission to improve and sustain care for people with inherited bleeding disorders around the world.

Key components of the Laboratory Science Program supported by the Talecris grant include:

IEQAS -- International External Quality Assessment Scheme

IEQAS focuses on improving and standardizing laboratory diagnosis of hemophilia worldwide. Participating laboratories test a uniform blood sample to verify their procedures and diagnosis. The process helps identify laboratories that require extra support. IEQAS partners with the World Health Organization (WHO) and the United Kingdom's National External Quality Assessment Scheme for Blood Coagulation Noun 1. blood coagulation - a process in which liquid blood is changed into a semisolid mass (a blood clot)
blood clotting

clotting, coagulation, curdling - the process of forming semisolid lumps in a liquid
.

International Train the Trainers Course

This program brings chief laboratory scientists from developing countries to the Royal Free Hospital in the U.K. for training on the latest techniques and scientific methodologies involved in the diagnosis of hemophilia and other bleeding disorders. The chief scientists then hold workshops to share their learnings with other laboratory scientists in their country or region.

Laboratory Workshops

WFH will hold workshops in 2007 designed to train laboratory specialists in developing countries around the world. Current locations for these workshops include sites in South America, Asia, and the Middle East.

Mark Skinner, President of the World Federation of Hemophilia, commented on the importance of the Talecris grant. "As WFH continues to expand its global outreach, we continue to focus heavily on creating access to quality care in developing countries. Critical to optimum care is the role the laboratory plays in diagnosis. The Talecris grant allows us to offer key components of our multifaceted Laboratory Science Program, and represents a solid example of a partnership with industry that will benefit people living with hemophilia around the world."

"Talecris is pleased to be partnering with the WFH," said Alberto Martinez, M.D., President and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  of Talecris Biotherapeutics. "Our commitment to the hemophilia community goes beyond our offering of Koate([R])-DVI (Antihemophilic Factor an·ti·he·mo·phil·ic factor
n. Abbr. AHF
See factor VIII.


antihemophilic factor (AHF, factor VIII)

Alphanate, Hemofil M, Koate-DVI, Kogenate FS, Monarc-M, Monoclate-P, Recombinate, ReFacto

 [Human]). Not only does this grant improve diagnosis and treatment care around the world, but it is consistent with our own internal commitment to laboratory excellence as demonstrated by our facilities in Raleigh, N.C., and Clayton, N.C."

About Koate([R])-DVI

Koate([R])-DVI (Antihemophilic Factor [Human]) is a plasma-derived product indicated for the treatment of classical hemophilia (hemophilia A hemophilia A
n.
Hemophilia due to deficiency of factor VIII, characterized by prolonged clotting time, decreased formation of thromboplastin, and diminished conversion of prothrombin.
) in which there is a demonstrated deficiency of activity of the plasma clotting factor clot·ting factor
n.
Any of various plasma components involved in the clotting of blood, including fibrinogen, prothrombin, thromboplastin, and calcium ion. Also called coagulation factor.
, factor VIII factor VIII
n.
A factor in the clotting of blood, a deficiency of which is associated with hemophilia A. Also called antihemophilic factor, antihemophilic globulin, antihemophilic globulin A,
. Koate([R])-DVI provides a means of temporarily replacing the missing clotting factor to correct or prevent bleeding episodes, or in order to perform emergency and elective surgery elective surgery Surgery Any operation that can be performed with advanced planning–eg, cholecystectomy, hernia repair, colonic resection, coronary artery bypass  on individuals with hemophilia. Koate([R])-DVI is a U.S. FDA-licensed product and is exported to over 40 countries around the world.

Koate([R])-DVI incorporates a double viral inactivation inactivation /in·ac·ti·va·tion/ (in-ak?ti-va´shun) the destruction of biological activity, as of a virus, by the action of heat or other agent.  in its manufacturing process using solvent/detergent and final container heating at 80[deg]C. More than two billion international units international units,
n.pl a unit of measurement that evaluates the potency of a substance. Because it measures potency instead of quantity, there is a different international unit-to-mg conversion ratio for each particular substance.
 of Koate([R])-DVI and its precursor product Koate([R]) HP have been infused into patients without a confirmed case of viral transmission. Allergic-type reactions may result from the administration of Antihemophilic Factor (Human) preparations. In the clinical study of Koate([R])-DVI, all adverse reactions adverse reactions,
n.pl unfavorable reactions resulting from administration of a local anesthetic; responsible factors include the drug used, concentration, and route of administration.
 were mild and included tingling tin·gle  
v. tin·gled, tin·gling, tin·gles

v.intr.
1. To have a prickling, stinging sensation, as from cold, a sharp slap, or excitement: tingled all over with joy.
 in the arm, ear, and face, blurred vision, headache, nausea, stomach ache, and jittery feeling.

As with all plasma-derived therapeutics, the potential to transmit infectious agents cannot be totally eliminated. For additional information on Koate([R])-DVI, please see full prescribing information at www.talecris.com/us/2.4.0_koate.aspx.

About Talecris Biotherapeutics: Inspiration. Dedication. Innovation.

Talecris Biotherapeutics is a global biotherapeutic and biotechnology company that discovers, develops and produces critical care treatments for people with life-threatening disorders in a variety of therapeutic areas including immunology, pulmonology pul·mo·nol·o·gy
n.
The branch of medicine that deals with diseases of the respiratory system.


pulmonology The study of the lungs and respiratory function
, and hemostasis hemostasis /he·mo·sta·sis/ (he?mo-sta´sis) (he-mos´tah-sis)
1. the arrest of bleeding by the physiological properties of vasoconstriction and coagulation or by surgical means.

2.
. Talecris is proudly building upon a 60-year legacy of innovation and a commitment to improving the lives of people who rely on its therapeutic products. With an emphasis on scientific inquiry and technological excellence, Talecris is expanding its current portfolio of products, programs, and services through its own world-class product development organization as well as through strategic initiatives that leverage its strengths with those of its partners.

Talecris, which earned revenues exceeding $1.1 billion in 2006, is headquartered in biotech hub Research Triangle Park, N.C., and employs more than 3,000 talented people worldwide.

To learn more about Talecris and how our employees are making a difference in the lives of patients and the healthcare community, visit www.talecris.com or www.talecrisplasma.com.
COPYRIGHT 2007 Business Wire
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Copyright 2007, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Date:May 3, 2007
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