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Takeda Pharmaceutical, Galaxy Biotech to Sign Licensing Agreement for HuL2G7, Investigational Agent for Cancer Treatment.


Tokyo, Japan, July 12, 2006 - (JCN JCN Japan Corporate News
JCN Journal of Cognitive Neuroscience
JCN Journal of Cardiovascular Nursing
JCN Journal of Christian Nursing
JCN Job Control Number
JCN Journal of Child Neurology
JCN joint communications network (US DoD) 
) - Takeda Pharmaceutical has signed a licensing agreement with Galaxy Biotech for HuL2G7, an anti-Hepatocyte Growth Factor (HGF HGF,
n See glucagon.
) monoclonal antibody monoclonal antibody, an antibody that is mass produced in the laboratory from a single clone and that recognizes only one antigen. Monoclonal antibodies are typically made by fusing a normally short-lived, antibody-producing B cell (see immunity) to a fast-growing  developed by Galaxy Biotech.

Under the agreement announced July 10, Takeda Pharmaceutical will licensed to exclusively develop, manufacture, and sell HuL2G7 worldwide. Takeda Pharmaceutical will make an upfront payment of $2 million, milestone payments on future development and royalties on product sales.

In addition, Takeda Pharmaceutical will provide Galaxy Biotech with millions of dollars for R&D over the next four years.

HuL2G7 is a humanized monoclonal antibody that inhibits the activities of HGF. It is reported that HGF is involved in tumor tumor: see neoplasm.  stasis stasis /sta·sis/ (sta´sis)
1. a stoppage or diminution of flow, as of blood or other body fluid.

2. a state of equilibrium among opposing forces.
 and growth, antiapoptosis and neoangiogenesis. In the recent studies, HuL2G7 has demonstrated an effect to promote tumor regression and improve survival.

Copyright [c] 2006 Japan Corporate News Network. All rights reserved.
COPYRIGHT 2006 Japan Corporate News Network K.K.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:JCNN News Summaries
Date:Jul 12, 2006
Words:140
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