TRADE NEWS: Agilent to Offer ETD Module for Ion Trap MS to Significantly Enhance De Novo Sequencing, PTM Analysis Results.PALO ALTO, Calif. -- Agilent Technologies Inc. (NYSE NYSE See: New York Stock Exchange :A) today announced a new electron transfer dissociation Electron transfer dissociation (ETD) is a method to fragment ions in a mass spectrometer.[1][2] Similar to electron capture dissociation, ETD induces fragmentation of cations (e.g. peptides or proteins) by transferring electrons to them. (ETD ETD abbr. estimated time of departure Noun 1. ETD - a system for screening luggage in airports; an agent passes a swab around or inside luggage and then runs the swab through a machine that can detect trace amounts of ) module for its top-of-the-line XCT XCT Xbox Canada Tournaments (gaming website) XCT Xbox Colombian Team (gaming) XCT X-Band Communications Transponder XCT Xtreme Cheer Technic (Quebec, Canada cheerleading) Ultra ion trap LC/MSD. The new module will significantly enhance the results for proteomics researchers doing de novo sequencing and post-translational modification (PTM PTM Post-Translational Modifications PTM Porsche Traction Management PTM Point-To-Multipoint PTM Please Tell Me PTM Packet Transfer Mode PTM Pulse-Time Modulation PTM Portugal The Man (band) PTM Predictive Technology Model ) analysis. ETD is a new method for performing peptide sequencing that uses a different mechanism to produce MS/MS MS/MS Tandem Mass Spectroscopy MS/MS Multistage Mass Spectrometry spectra and has several advantages when compared with traditional Collision Activated Dissociation (CAD). Ions are formed outside of the ion trap, allowing full mass range to be collected and eliminating the 1/3 low-mass cutoff restriction of CAD ion trap analysis. Fragmentation by ETD provides a complete series of c and z ions and direct read out of amino acid sequence. For PTM studies, the ETD process retains phosphorylation phosphorylation, chemical process in which a phosphate group is added to an organic molecule. In living cells phosphorylation is associated with respiration, which takes place in the cell's mitochondria, and photosynthesis, which takes place in the chloroplasts. sites on a peptide fragment, making identification of sites simple and straightforward. "The ETD option will be available with our new LC/MSD trap XCT Ultra in early 2006," said Taia Ergueta, Agilent business manager for proteomics. "We're also offering an upgrade path on existing XCT instruments, making this useful performance option available to a wider range of users." About Agilent Technologies Agilent Technologies Inc. (NYSE:A) is the world's premier measurement company and a technology leader in communications, electronics, life sciences and chemical analysis. The company's 28,000 employees serve customers in more than 110 countries. Agilent had net revenue of $7.2 billion in fiscal year 2004. Information about Agilent is available on the Web at www.agilent.com. NOTE TO EDITORS: Press releases, photography and other information can be accessed on the Agilent Life Sciences and Chemical Analysis newsroom at www.agilent.com/about/newsroom/lsca. Further technology, corporate citizenship and executive news is available on the Agilent news site at www.agilent.com/go/news. |
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