TRADE NEWS: Agilent Technologies Expands Use of HPLC Chip to Entire LC Mass Spectrometry Portfolio.Chip with LC/MS LC/MS Liquid Chromatography/Mass Spectrometry Now Performs Small Molecule Analysis CHICAGO -- Agilent Technologies (NYSE NYSE See: New York Stock Exchange :A) today expanded use of its revolutionary, high-performance liquid chromatography (HPLC HPLC high-performance liquid chromatography. HPLC high performance liquid chromatography. HPLC High-performance liquid chromatography Lab instrumentation A highly sensitive analytic method in which analytes are placed ) chip to its triple quadrupole A quadrupole is one of a sequence of configurations of electric charge or gravitational mass that can exist in ideal form, but it is usually just part of a multipole expansion of a more complex structure reflecting various orders of complexity. (QQQ QQQ The Nasdaq-100 Index Tracking Stock. This is a tracking stock which trades like an index mutual fund which follows the Nasdaq 100 index. It trades continuously. QQQ ) and quadrupole-time of flight (Q-TOF) mass spectrometers. The move enables both of these chip/mass spectrometer systems to perform small molecule analysis and completes the chip's expansion across Agilent's entire liquid chromatography/mass spectrometry (LC/MS) portfolio. Agilent's HPLC chip technology is an innovative form of liquid chromatography separation that replaces conventional LC nanoflow column and microvalves with a simple, compact microfluidics chip. Smaller than a credit card, the chip seamlessly integrates the sample enrichment and separation capability of a nanoflow LC system with the single emitter per instrument and intricate connections used for electrospray mass spectrometry mass spectrometry or mass spectroscopy Analytic technique by which chemical substances are identified by sorting gaseous ions by mass using electric and magnetic fields. . The technology eliminates 50 percent of the fittings and connections typically required in nanoflow LC/MS systems, dramatically reducing the possibility of leaks and dead volumes, and significantly improving ease-of-use, sensitivity, productivity and reliability during analysis. Agilent's HPLC Chip technology delivers stable, reproducible nanospray, critical for high-sensitivity quantitative QQQ applications for small molecules. The expansion announced today enables researchers to move beyond the HPLC chip's early protein-identification applications to the small molecule arena. "Where sample size is limited, quantitative nanospray on the QQQ in particular will offer special opportunities, providing substantial savings to customers in sample preparation alone," said Agilent's Fred Strohmeier, vice president and general manager, Liquid Phase Separations Division. "It will have special use for life sciences, environmental and forensic applications, where researchers often deal with low amounts of sample. "For these applications, conventional nanospray isn't reliable enough for routine use and is difficult to implement and maintain," said Strohmeier. "With the HPLC chip, in combination with Agilent's LC/MS portfolio, it's finally accessible for these applications -- and in a remarkably easy-to-use format." For further information about Agilent's life sciences and chemical analysis solutions, visit Agilent online at www.chem.agilent.com. About the Products Mass spectrometry is used to identify organic compounds and contaminants through analysis of their ion fragments. It is used in food safety, environmental testing, forensics See computer forensics. and proteomics research, as well as drug discovery, development and manufacturing QA/QC QA/QC Quality Assurance/Quality Control . The Agilent 6410 Triple Quadrupole provides femtogram-level sensitivity -- comparable to the most expensive instruments of this class -- along with Agilent reliability and a 30 percent to 50 percent lower price. It is used primarily for environmental, food safety, forensics and pharmaceutical applications. The Agilent 6510 Q-TOF provides superior analytical performance compared with the most expensive high-performance Q-TOF instruments. It simultaneously offers attomole sensitivity, routine mass accuracy better than 3 ppm, and 3.5 orders of magnitude in-spectra dynamic range. It enables fast data acquisition at 20 spectra/second or 1 MS and 5 MS/MS MS/MS Tandem Mass Spectroscopy MS/MS Multistage Mass Spectrometry per second in data-dependent mode. For more information about these products, contact your sales representative or the Agilent Customer Call Center (phone numbers by country available online at www.chem.agilent.com/scripts/cag_feedback.asp). About Agilent in Mass Spectrometry Agilent is a leading provider of GC/MS GC/MS Gas Chromatograph/Mass Spectrometer GC/MS Gas Chromatograph/Mass Spectrometry GC/MS Gas Chromatograph/Mass Spectrograph , LC/MS and ICP-MS ICP-MS Inductively Coupled Plasma Mass Spectroscopy technologies for organic and inorganic spectroscopy. Among the company's key products are the Agilent 5973 and the 5975C (announced today) inert GC/MSDs as well as the 7500 Series ICP-MS systems and the Agilent 6000 Series LC/MS single quadrupole, triple quadrupole, ion trap, TOF (Top Of Form) The beginning of a physical paper form. To position paper in many printers, the printer is turned offline, the forms are aligned properly and the TOF button is pressed. and Q-TOF instruments. Agilent provides the innovative HPLC-Chip/MS technology and the broadest range of ion sources in the industry. As a leader in separations and software, Agilent can address the entire customer workflow from sample introduction through data analysis. About Agilent Technologies Agilent Technologies (NYSE:A) is the world's premier measurement company and a technology leader in communications, electronics, life sciences and chemical analysis. The company's 19,000 employees serve customers in more than 110 countries. Agilent had net revenue of $5.0 billion in fiscal 2006. Information about Agilent is available on the Web at www.agilent.com. NOTE TO EDITORS: Further technology, corporate citizenship Corporate Citizenship The extent to which businesses are socially responsible in meeting legal, ethical and economic responsibilities placed on them by shareholders. The aim it to create higher standards of living and quality of life in the community in which it operates, while and executive news is available on the Agilent news site at www.agilent.com/go/news. |
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