TRADE NEWS: Agilent Technologies Announces Availability of Industry's Highest-Performance Quadrupole Time-of-Flight LC/MS; System Sets New Standard for Sensitivity, Speed and Mass Accuracy.SEATTLE -- Agilent Technologies This article needs sources or references that appear in reliable, third-party publications. Alone, primary sources and sources affiliated with the subject of this article are not sufficient for an accurate encyclopedia article. Inc. (NYSE NYSE See: New York Stock Exchange :A) today announced the availability its quadrupole A quadrupole is one of a sequence of configurations of electric charge or gravitational mass that can exist in ideal form, but it is usually just part of a multipole expansion of a more complex structure reflecting various orders of complexity. time-of-flight (Q-TOF) liquid chromatograph/mass spectrometer (LC/MS LC/MS Liquid Chromatography/Mass Spectrometry ), a key addition to the company's new 6000 Series of LC/MS systems. With a tenfold sensitivity advantage over other instruments in its class, the fastest data-dependent acquisition speed and better than 2 ppm mass accuracy in MS mode, Agilent's bench-top 6510 Q-TOF LC/MS sets a new standard for analytical performance. Q-TOF mass spectrometers are widely used to identify and characterize compounds in complex samples, bringing the power of accurate mass to MS/MS MS/MS Tandem Mass Spectroscopy MS/MS Multistage Mass Spectrometry experiments. Important applications in drug discovery include protein identification and characterization, biomarker discovery Biomarker discovery is the process by which biomarkers are discovered. It is a medical term. Many commonly used blood tests in medicine are biomarkers. The way that these tests have been found can be seen as biomarker discovery. and metabolite metabolite, organic compound that is a starting material in, an intermediate in, or an end product of metabolism. Starting materials are substances, usually small and of simple structure, absorbed by the organism as food. identification. In food-safety testing and environmental and forensic analysis, Q-TOF technology is applied to structural studies, compound screening and confirmation. "Q-TOF LC/MS is a premier qualitative analysis Qualitative Analysis Securities analysis that uses subjective judgment based on nonquantifiable information, such as management expertise, industry cycles, strength of research and development, and labor relations. technology, but customers have historically faced a trade-off between sensitivity and mass accuracy," said Taia Ergueta, general manager of Agilent's mass spectrometry mass spectrometry or mass spectroscopy Analytic technique by which chemical substances are identified by sorting gaseous ions by mass using electric and magnetic fields. business. "The combination of mass accuracy, speed and sensitivity of Agilent's 6510 enables leading-edge workflows such as profiling, which can greatly improve the results in proteomics, metabolomics and metabolite identification. The system can also advance other research by allowing customers to uncover and characterize more compounds in challenging samples with greater speed, efficiency and confidence." Instrument complexity and the need for frequent servicing have prevented earlier Q-TOF technology from achieving its full potential. With the 6510, Agilent has delivered a Q-TOF with industry-leading analytical performance, along with Agilent reliability and unsurpassed simplicity of use. The Agilent 6510 facilitates the identification of low-abundance compounds via attomole-level sensitivity -- unmatched among Q-TOFs -- and a wide in-spectrum dynamic range (three to four orders of magnitude). Scanning speeds of up to 20 full-scan spectra per second increase throughput and allow the system to keep pace with the fastest LC systems available, including Agilent's 1200 Series LC. With mass accuracy approaching that of Fourier Transform MS (less than 2 ppm MS and 5 ppm MS/MS) and Agilent's autotune technology, the 6510 allows any operator to identify unknowns with great confidence. Like all of Agilent's LC/MS systems, the 6510 is compatible with the broadest range of ion sources, including Agilent's HPLC-Chip/MS source, which supports robust nanospray LC/MS performance; and the proprietary multimode ion source, which increases throughput and productivity by reducing the need for repeated experimental runs. Agilent's MassHunter Workstation software provides single-point instrument control and rapid resolution MS data processing capabilities to the 6510, simplifying operation and further improving productivity. Advanced, application-specific software packages, including MassHunter Profiling software, Spectrum Mill and GeneSpring MS, enable fast, sensitive extraction of data, and quickly convert complex analyses into answers about the identity and composition of proteins, metabolites Metabolites Substances produced by metabolism or by a metabolic process. Mentioned in: Interactions , biomarkers and impurities. Built on open architecture and industry standards, the MassHunter Workstation allows users to integrate the 6510 into existing IT environments or Agilent's own OpenLab system for centralized data management. For more information about the Agilent 6510 Q-TOF, contact your sales representative, the Agilent Customer Call Center (phone numbers by country available online at www.chem.agilent.com/scripts/cag_feedback.asp), or visit Agilent online at www.agilent.com/chem/QTOF. Availability The Agilent 6510 Q-TOF LC/MS is available now, with shipments beginning in September 2006. Agilent in Mass Spectrometry Agilent is a leading provider of GC/MS GC/MS Gas Chromatograph/Mass Spectrometer GC/MS Gas Chromatograph/Mass Spectrometry GC/MS Gas Chromatograph/Mass Spectrograph , LC/MS and ICP-MS ICP-MS Inductively Coupled Plasma Mass Spectroscopy technologies for organic and inorganic spectroscopy. Among the company's key products are the 5973 and 5975 inert MSDs, the 7500 Series ICP-MS systems, and the new Agilent 6000 Series LC/MS triple quadrupole, ion trap, time-of-flight and quadrupole time-of-flight instruments. Agilent provides innovative HPLC-Chip/MS technology and the broadest range of ion sources in the industry. As a leader in separations and software, Agilent can address the entire customer workflow from sample introduction through data analysis. About Agilent Technologies Agilent Technologies Inc. (NYSE:A) is the world's premier measurement company and a technology leader in communications, electronics, life sciences and chemical analysis. The company's 20,000 employees serve customers in more than 110 countries. Agilent had net revenue of $5.1 billion in fiscal 2005. Information about Agilent is available on the Web at www.agilent.com. NOTE TO EDITORS: Press releases, photography (Image 81 in Image Library) and other information can be accessed on the Agilent Life Sciences and Chemical Analysis newsroom at www.agilent.com/about/newsroom/lsca. Further technology, corporate citizenship Corporate Citizenship The extent to which businesses are socially responsible in meeting legal, ethical and economic responsibilities placed on them by shareholders. The aim it to create higher standards of living and quality of life in the community in which it operates, while and executive news is available on the Agilent news site at www.agilent.com/go/news. |
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