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Study Identifies Factors to Predict Survival After Liver Transplant.

A new model based on specific characteristics of liver donors and recipients may help predict survival after liver transplantation, according to a new study by physicians with the Veterans Affairs Puget Sound Health Care System in Seattle. Results are published in the November issue of Liver Transplantation.

"This model could be used to inform liver transplant candidates and their doctors what post-transplant survival would be expected when a given donor is offered and may be particularly helpful in marginal or high-risk donors," said George Ioannou, M.D., M.S., in a journal press release. Ioannou found that the donor age, cold ischemia time, recipient MELD score, and cause of liver disease have the greatest impact on survival.

However, the best model for patients without hepatitis C included donor age, cold ischemia time, gender, race/ethnicity, recipient age, BMI, MELD score, status at time of transplantation, diabetes mellitus, cause of liver disease, and serum albumin. For patients with hepatitis C, the best model included the same donor characteristics, and all recipient characteristics except cause of liver disease and serum albumin.

Link: www.sciencedaily.com/releases/2006/11/061102110304.htm (11/29/06)
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Title Annotation:medical research
Publication:Transplant News
Article Type:Brief article
Geographic Code:1USA
Date:Dec 1, 2006
Words:191
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