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Studies Presented at American Academy of Dermatology in New Orleans Reaffirm Effectiveness GHK Copper Peptide Technology.


Business Editors, Health/Medical Writers

REDMOND, Wash.--(BW HealthWire)--Feb. 26, 2002

ProCyte Corporation, (OTCBB OTCBB

See OTC Bulletin Board (OTCBB).
: PRCY), today announced that four new independent studies presented at the AAD AAD American Academy of Dermatology.
AAD American Association of Dermatology
 in New Orleans New Orleans (ôr`lēənz –lənz, ôrlēnz`), city (2006 pop. 187,525), coextensive with Orleans parish, SE La., between the Mississippi River and Lake Pontchartrain, 107 mi (172 km) by water from the river mouth; founded  have shown significant results in improving various skin conditions when using the Company's patented GHK GHK Goldman-Hodgkin-Katz (equation)
GHK Gush Katif, Israel - Domestic Airfield (airport code)
GHK Global Hot Key
GHK Group Hot Key
 Copper Peptide compound.

Areas evaluated included repair of signs of photoaging pho·to·ag·ing
n.
1. The process by which skin is changed or damaged as a result of exposure to ultraviolet radiation in sunlight and other sources.

2.
 (sun damage), reducing fine lines History
Fine Lines is a new Japanese rock band that consist two members from band called Husking Bee. Their dual emotionally charged vocalists, and impressive musicianship of the members: Tetsuya Kudo on bass, Kazuya Hirabayashi on guitar and vocals, George Kurosawa on guitar
 and wrinkles and improving skin texture and firmness.

The first study by J.J. Leyden, MD, et al, compared a GHK Copper Peptide cream to a Vitamin K vitamin K

Any of several fat-soluble compounds essential for the clotting of blood. A deficiency of vitamin K in the body leads to an increase in clotting time. In 1929 a previously unrecognized fat-soluble substance present in green leafy vegetables was found to be required
 containing product in a series of 3 double blind studies involving 108 patients. The GHK Copper Peptide cream was found to significantly improve the eye area appearance and was better than the Vitamin K treatment for several efficacy and tolerance criteria such as, fine lines and skin firmness.

A second study by J.J. Leyden, MD, et al, compared GHK Copper Peptide facial cream to another popular skin care treatment as well as a placebo. There were a combined total of 86 patients in the eight and twelve week double blind studies. The studies showed skin treated with GHK Copper Peptide demonstrated rapid, visual overall improvements in skin roughness, clarity, fine lines and wrinkling and overall photodamage.

Also presented was a study evaluating the ProCyte patented GHK Copper Peptide compound in a liquid foundation and cream concealer con·ceal·er  
n.
1. One that conceals.

2. A facial cosmetic used to cover blemished skin.
 over an 8-week period. The evaluations included visual grading of bare skin, biomechanical measurements for viscoelastic Adj. 1. viscoelastic - having viscous as well as elastic properties
natural philosophy, physics - the science of matter and energy and their interactions; "his favorite subject was physics"
 properties and subjective assessment including digital photography with significant improvements in all visual evaluations at 2 weeks. Additionally, viscoelastic properties improved and there was an increase of epidermal Epidermal
Referring to the thin outermost layer of the skin, itself made up of several layers, that covers and protects the underlying dermis (skin).

Mentioned in: Antiangiogenic Therapy, Histiocytosis X


epidermal
 thickness.

The fourth study conducted by Thierry Oddos, et al, assessed the importance of complexed GHK Copper Peptide versus copper chloride Copper forms two stable chlorides:
  • Copper(I) chloride (cuprous chloride), CuCl, mineral name nantokite.
  • Copper(II) chloride (cupric chloride), CuCl2, mineral name eriochalcite.
Detailed information on each of these compounds is found on the specific pages linked above.
 (an inorganic salt), copper gluconate Copper gluconate is the copper salt of D-gluconic acid. Uses
  • Dietary supplement -- metabolizable copper to treat copper deficiency.
  • Used to treat acne vulgaris, common cold, hypertension, premature labor, Leishmaniasis, visceral postoperative complications.
 (an organic salt) and non-complexed copper with peptides in the development of new collagen. The patented complexed GHK Copper Peptide compound was shown to significantly stimulate collagen synthesis. Both copper salts failed to stimulate collagen synthesis. Treatment with non-complexed copper with peptides and copper chloride as separate ingredients within the same formulation at the same ratio as the GHK Copper Peptide compound did not stimulate collagen synthesis.

"The studies reaffirm our early work and current physician and consumer satisfaction with the performance of products containing GHK Copper Peptide in improving the visual effects of aging. The comparison of the patented ProCyte GHK Copper Peptide compound to organic and inorganic copper salts confirms once again the work on which ProCyte is founded," said Jack Clifford, President & CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. . "While others may claim they have a dynamic copper peptide compound, it takes more than copper and random amino acids thrown into a formulation to establish a molecularly complexed tripeptide tripeptide /tri·pep·tide/ (tri-pep´tid) a peptide that on hydrolysis yields three amino acids.

tripeptide

a peptide formed from three amino acids.
 copper that is similar to the natural system within the body. The GHK Peptide system used to transport copper is a critical part of ProCyte's innovative research and patent estate and why our products are so effective. The use of our patented GHK Copper Peptide is gaining popularly in skin care and these studies reaffirm the reasons why."

ProCyte markets its Neova(R) Therapy brand of product directly to dermatologists and plastic surgeons through its own sales force. Products can also be purchased through physician Internet sites like dermadoctor.com. ProCyte has also licensed its technology to Neutrogena, a Johnson and Johnson Company that sells products under the Visibly Firm(TM) brand in the mass retail market.

Based on continuing research efforts, ProCyte expects to initiate new clinical study probes in targeted dermatology and oral applications for its GHK Copper Peptide compound. In conjunction with the plastic and cosmetic surgery cosmetic surgery, plastic surgery for cosmetic purposes, such as the improvement of the appearance of the face by removing wrinkles or reshaping the nose.  market, the Company is also exploring the use of GHK Copper Peptide in conjunction with injectable in·ject·a·ble
adj.
Capable of being injected. Used of a drug.

n.
A drug or medicine that can be injected.
 collagen.

ProCyte Corporation is a healthcare products company that develops and markets products for skin health, hair care and wound care. The Company's comprehensive therapeutic and anti-aging skin care lines include products for post-procedure treatments and anti-aging applications, as well as products for thinning hair. Many products incorporate the ProCyte patented, clinically proven Copper Peptide technology, which it markets directly to Dermatologists and plastic surgeons through the Company's own sales force and through distribution partners and licensees for wound care and consumer market segments.

ProCyte will announce its fourth quarter and yearend 2001 financial results on Thursday February 28. There is a conference call scheduled for 1pm Pacific Standard Time on the 28th. The call in number is 800/261-9419 and the access code is 44595. A replay is available until March 4th by calling 800/270-2092.

This release may contain forward-looking statements relating to the research, development, commercialization, production, marketing and distribution of the Company's products and future operating results that are subject to certain risks and uncertainties which could cause actual results to differ materially from those projected. The words "believe," "expect," "intend," "anticipate," variations of such words, and similar expressions identify forward-looking statements, but their absence does not mean that the statement is not forward-looking. These statements are not guarantees of future performance and are subject to certain risks, uncertainties and assumptions that are difficult to predict. (Factors that could affect the Company's actual results include its ability to develop, commercialize and produce new products, the market acceptance of existing and potential future products, the availability, cost and timely delivery of materials and services from and performance of third party suppliers, manufacturers, distributors, licensees and other collaborative partners, the satisfaction of regulatory requirements, and the receipt, timing, terms and conditions of required regulatory approvals.) Reference is made to the Company's latest Quarterly Report on Form 10Q or Form 10K filed with the Securities and Exchange Commission for a more detailed description of such factors. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this release. The Company undertakes no obligation to publicly update any forward-looking statement to reflect new information, events or circumstances after the date of this release or to reflect the occurrence of unanticipated events.
COPYRIGHT 2002 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2002, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Geographic Code:1USA
Date:Feb 26, 2002
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