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Sticky treatment for staph infections.

Honey made by bees pollinating a New Zealand New Zealand (zē`lənd), island country (2005 est. pop. 4,035,000), 104,454 sq mi (270,534 sq km), in the S Pacific Ocean, over 1,000 mi (1,600 km) SE of Australia. The capital is Wellington; the largest city and leading port is Auckland.  bush can gum up bacteria, offering a potential new therapy for difficult-to-treat infections.

A scourge of hospitals, the pathogen called methicillin-resistant Staphylococcus aureus methicillin-resistant Staphylococcus aureus Methicillin-aminoglycoside resistant Staphylococcus aureus, MRSA An organism with multiple antibiotic resistances–eg, aminoglycosides, chloramphenicol, clindamycin, erythromycin, rifampin, tetracycline,  defies most antibiotics. But a handful of ease reports notes that slather-ing manuka-bush honey on wound dressings seems to reverse staph infection Staph infection
Infection with Staphylococcus bacteria. These bacteria can infect any part of the body.

Mentioned in: Cephalosporins
.

The edible honey failed to sell in New Zealand because of its bitter taste, but for hospitals, it may be just what the doctor ordered.

Rose Cooper of the University of Wales Affiliated institutions
  • Cardiff University
Cardiff was once a full member of the University but has now left (though it retains some ties). When Cardiff left, it merged with the University of Wales College of Medicine (which was also a former member).
 Institute at Cardiff turned an electron microscope electron microscope: see microscope.  on S. aureus The aureus (pl. aurei) was a gold coin of ancient Rome valued at 25 silver denarii. The aureus was regularly issued from the 1st century BC to the beginning of the 4th century AD, when it was replaced by the solidus.  growing in petri dishes and saw that many of the bacteria got stuck after encountering manuka honey. The cells began to divide but then stopped. "It looks like they can't complete the cell cycle" she says.

Cooper also studied the bug's reaction to syrup that contained only the honey's sugars. This fake honey didn't prevent S. aureus cells from dividing normally. "Something in the honey besides the sugars" stops the cells, says Cooper. Her team is now trying to identify this component.

Ancient Egyptian physicians famously treated wounds with honey, but modern doctors "are a bit reticent" about doing the same, says Cooper. However, sterile manuka honey has been available by prescription in the United Kingdom since 2004, and a hospital in Liverpool will soon launch a trial of the sticky stuff.

If the study goes well, manuka honey "could have a key role to play in controlling hospital-borne infections," says Cooper.
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Title Annotation:ANTIBIOTIC RESISTANCE
Author:Vastag, B.
Publication:Science News
Date:Jun 9, 2007
Words:247
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