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Stem cells from human fat tissue used for 'biologial' pacemaker.

Stem cells stem cells, unspecialized human or animal cells that can produce mature specialized body cells and at the same time replicate themselves. Embryonic stem cells are derived from a blastocyst (the blastula typical of placental mammals; see embryo), which is very young  from a type of human fat tissue may one day be able to reverse the electrical problems in the heart that pacemakers now correct, according to Japanese scientists.

Researchers grew "beating" cells with properties similar to the heart's conductive tissue from stem cells taken from the brown fat tissue of mice. They then injected them into rodents with reduced heart rates caused by electrical signaling problems known as atrioventricular atrioventricular /atrio·ven·tric·u·lar/ (-ven-trik´u-ler) pertaining to both an atrium and a ventricle of the heart.

a·tri·o·ven·tric·u·lar
adj. Abbr.
 (AV) block, according to HealthDay News.

After a week, the AV block was completely reversed or partially reversed in half the test mice, the scientists reported, adding that no change was observed in the control mice.

"Electronic pacemakers are often used as palliative therapy palliative therapy Palliative treatment Medtalk Any treatment of a terminally ill Pt intended to alleviate pain and suffering, without performing aggressive–'heroic' procedures; PT does not alter course of disease, but improves the quality of life before  for people who have conduction problems with the electrical signals that govern the heart beat. However, that therapy has several shortcomings A shortcoming is a character flaw.

Shortcomings may also be:
  • Shortcomings (SATC episode), an episode of the television series Sex and the City
, including possible malfunction and the need for repeated replacement of the devices's power packs and eletrodes," the study's lead author Dr. Toshiniao Takahashi, a research fellow at Chiba University Graduate School of Medicine in Chiba, Japan, said in an American Heart Association American Heart Association (AHA),
n.pr a national voluntary health agency that has the goal of increasing public and medical awareness of cardiovascular diseases and stroke, and thereby reducing the number of associated deaths and disabilities.
 news release. "Cell therapy could overcome those problems and provide a possible cure for conductive disease. Our goal is to create a biological pacemaker."
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Publication:Transplant News
Date:Aug 1, 2009
Words:202
Previous Article:Johns Hopkins researchers report successfully creating stem cells from developing sperm from fruit fly.
Next Article:National Institutes of Health.
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