Statin therapy for diabetics.
The cholesterol-lowering medicine Lipitor helps protect people with diabetes from heart attacks and strokes, according to a large study presented at the recent annual meeting of the American Diabetes Association The American Diabetes Association, or the ADA, is an American health organization providing diabetes research, information and advocacy. Founded in 1940, the American Diabetes Association conducts programs in all 50 states and the District of Columbia, reaching hundreds of .
The Collaborative Atorvastatin atorvastatin /ator·va·stat·in/ (ah-tor?vah-stat´in) an antihyperlipidemic agent that acts by inhibiting cholesterol synthesis, used as the calcium salt in the treatment of hypercholesterolemia and other forms of dyslipidemia. Diabetes Study (CARDS) evaluated nearly 3,000 patients with type 2 diabetes type 2 diabetes
See diabetes mellitus. , no history of heart disease, and relatively low levels of cholesterol. Data show that patients who took Lipitor had a 37 percent reduction in major cardiovascular events and experienced 48 percent fewer strokes compared to those who received placebos.
The trial was halted nearly two years earlier than planned due to the significant benefits among patients taking the active drug.
"This important study has demonstrated that lowering cholesterol with atorvastatin in patients with diabetes--even those whose LDL LDL - ["LDL: A Logic-Based Data-Language", S. Tsur et al, Proc VLDB 1986, Kyoto Japan, Aug 1986, pp.33-41]. , or 'bad' cholesterol, levels were relatively low--will result in a dramatic cardiovascular benefit," said CARDS co-principal investigator Professor Helen Colhoun of University College, Dublin, Ireland. "CARDS demonstrates that statin stat·in
Any of a class of drugs that inhibit a key enzyme involved in the synthesis of cholesterol and promote receptor binding of LDL cholesterol, resulting in decreased levels of serum cholesterol. therapy can be of great benefit to the vast majority of diabetes patients."
American Diabetes Association guidelines recommend that adults with type 2 diabetes should be considered for statin therapy regardless of their LDL levels.