Squalus Biotech Inc. Commences Trading Under SQBT and Begins Commercialization of its Cancer-Fighting Product Squalamatrix.LAS VEGAS -- Squalus Biotech Inc. (Pink Sheets:SQBT) announced today that the company has commenced trading on the Pink Sheets under the ticker symbol SQBT. Squalus Biotech Inc. is a development stage company conducting discovery, development, production, and marketing of novel and unique therapeutics for cancer and other angiogenesis related diseases. Squalus Biotech focuses on pursuing strategic alliances with major pharmaceutical companies to collaborate on human clinical trials, FDA FDA abbr. Food and Drug Administration FDA, n.pr See Food and Drug Administration. FDA, n.pr the abbreviation for the Food and Drug Administration. approval, manufacturing, and marketing of novel cancer drugs. Squalamatrix(TM) is the company's patented trademark designation of a group of biologically active group of substances extracted from the water-soluble portion of shark liver tissue. Sharks have been in the pharmacopoeia pharmacopoeia or pharmocopeia (fär'məkəpē`ə), authoritative publication designating the properties, action, use, dosage, and standards of strength and purity of drugs. of alternative and aryuvedic medicine around the world in various forms for centuries. Healing properties and tonic effects of various forms and derivatives of components of shark liver and cartilage have been documented in literature of many languages. Remedies in various forms can be found in China, the Philippines, Scandinavia, Europe, the former soviet republic of Georgia, and more recently Canada and the U.S. These derivatives in the form of chondroitin sulfate, glucosamine glucosamine /glu·co·sa·mine/ (gloo-ko´sah-men) an amino derivative of glucose, occurring in glycosaminoglycans and a variety of complex polysaccharides such as blood group substances. , squalene squalene (skwäˑ·lēn), n a popular traditional Asian remedy derived from the liver oil of sharks. , retinol retinol: see Vitamin A under vitamin. (Vitamin A) and akyglycerols have all been shown to exhibit varying degrees of effectiveness and positive anecdotal accounts, but with very few controlled double blind reported studies or basic experimental data to validate their claims Larry Raithaus, M.D., FACS FACS Fellow of the American College of Surgeons. FACS abbr. Fellow of the American College of Surgeons FACS fluorescence-activated cell sorter. , a Board Certified Urologist, who has a clinical practice of Urology in Hawaii, is President, CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. and co-founder of Squalus Biotech Inc. He is the developer and inventor of SQUALAMATRIX(TM), the company's patented shark liver extract formula, which contains Squalamine, an aminosterol that has known anti-angiogenic effects, as well as at least 10 other aminosterols. He stated, "Bringing the company public at this time supports the company's growth strategy while capitalizing on its participation in the field of angiogenesis. This field has developed into one of the most promising approaches in cancer therapeutics. Genentech's announcement of its successful human clinical trial of Avastin in metastatic Metastatic The term used to describe a secondary cancer, or one that has spread from one area of the body to another. Mentioned in: Coagulation Disorders metastatic pertaining to or of the nature of a metastasis. colon cancer propelled its stock market valuation by $8.7 billion in a single day. Currently several anti-angiogenic compounds are under extensive human clinical trials. These include such anti-angiogenic drugs as Squalamine Lactate Lactate A salt or ester of lactic acid (CH3CHOHCOOH). In lactates, the acidic hydrogen of the carboxyl group has been replaced by a metal or an organic radical. Lactates are optically active, with a chiral center at carbon 2. produced by Genaera Corp. and Avastin produced by Genentech." Angiogenesis has long been suspected in playing a primary role in many pathological conditions involving the increased formation of blood vessels. These include Cancer, AIDS-related Kaposi's Sarcoma, Rheumatoid Arthritis, Macular Degeneration and many other diseases. In cancer, discrete solid tumor masses appear when malignant cells provoke the surrounding vascular network to expand in order to supply its increasing nutritional needs, thus nurturing the potential for the development of metastases Metastasis (plural, metastases) A tumor growth or deposit that has spread via lymph or blood to an area of the body remote from the primary tumor. Mentioned in: Malignant Melanoma . The inhibition of blood vessel formation is an especially useful mechanism in the treatment of these conditions The management team is comprised of a group of highly skilled executive, scientific, and operational personnel: Dr. Larry Raithaus, M.D. FACS--President and CEO In 1993, studies were performed which established the immune stimulation effects and the radiation protection effects of a preparation derived from the lyophilized ly·oph·i·lize tr.v. ly·oph·i·lized, ly·oph·i·liz·ing, ly·oph·i·liz·es To freeze-dry (blood plasma or other biological substances). [lyophil(ic) + -ize. water-soluble portion of the liver of the shark. Based upon these studies a U.S. patent was issued for the process as well as the applications of the product. Mr. Greg Shafransky--Vice President of Marketing and Sales Mr. Shafransky has been involved in nutraceutical/health food industry in product sales and marketing since 1989. Mr. Shafransky brings to the team over 15 years of product development, marketing and financing experience. Prof. Kin-Ping Wong, PhD will be joining the company to head up the Research and Development Division He has published extensively in the field of protein folding, ribosome ribosome: see cell; nucleic acid. ribosome Tiny particle, the site of protein synthesis, that is present in large numbers in living cells. They occur both as free particles within cells and, in eukaryotes, as particles attached to the membranes of assembly, and angiogenesis His current research focuses on the discovery and development of novel anti-angiogenic therapeutics targeting the vascular network for the treatment of neovascular-based diseases such as cancer, macular degeneration -- a leading cause of blindness in the elderly -- and arthritis. For more information on Squalus Biotech Corporation, please visit the company's Web site at www.squalusbiotech.com. This press release contains forward-looking statements as that term is defined in the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and of 1995. Such forward-looking statements are subject to risks and uncertainties, which could cause actual results to differ materially from those anticipated. The information set forth herein should be read in light of such risks. The Company assumes no obligation to update the information contained in this press release. |
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