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Sosei UK Subsidiary Starts Phase IIb Clinical Trial of AD 452, Investigational Drug for Treating Rheumatoid Arthritis.


Tokyo, Japan, Sept 6, 2005 - (JCNN JCNN Japan Corporate News Network ) - Sosei, a Japanese biopharmaceutical company, announced on September 5 that its wholly owned UK subsidiary Arakis has started a phase IIb dose-ranging study of AD 452, an investigational drug for the treatment of rheumatoid arthritis rheumatoid arthritis

Chronic, progressive autoimmune disease causing connective-tissue inflammation, mostly in synovial joints. It can occur at any age, is more common in women, and has an unpredictable course.
 (RA).

AD 452 is a low-molecular disease modifying anti-rheumatic drug (DMARD Disease Modifying Anti-Rheumatic Drugs (DMARDs)
A class of antirheumatic drugs, including chloroquine, methotrexate, cyclosporine, and gold compounds, that influence the disease process itself and do not only treat its symptoms.

Mentioned in: Antirheumatic Drugs
) that is expected to reduce joint inflammation, destruction and pain while preserving mobility.

Arakis completed a phase IIa clinical trial of AD 452 in April and obtained positive results. It is estimated that there are about 6 million people with RA in Europe, the US and Japan.

The global market for RA drugs is presently estimated at 600 billion yen ($5.5 bil), and is expected to exceed 1 trillion yen ($10.5 bil) in 2008.

Source: JCN JCN Japan Corporate News
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Publication:JCNN News Summaries
Date:Sep 6, 2005
Words:144
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