Smoking more than one pack of cigarettes a day increases the risk of cardiovascular disease.
* Increasing platelet adhesion and aggregation, increasing risk of thrombosis.
* Increasing blood viscosity.
* Increasing serum fibrinogen concentration, increasing risk of thrombosis.
* Damaging vascular endothelium (eg, from carbon monoxide and polycyclic aromatic hydrocarbons).
* Oxidizing LDL, increasing risk of atherosclerosis.
* Reducing HDL concentration.
* Increasing oxygen demand of the myocardium while simultaneously reducing the blood's capacity for carrying oxygen.
From Keil U: Coronary artery disease: the role of lipids, hypertension and smoking. Basic Res Cardiol 2000 (Suppl I); 95:152-158.
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|Publication:||Southern Medical Journal|
|Article Type:||Brief Article|
|Date:||Mar 1, 2002|
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