Shin Nippon Biomedical Laboratories Obtains New Knowledge on Drug-metabolizing Enzyme Cytochrome P450.Tokyo, Japan, May 9, 2006 - (JCN JCN Japan Corporate News JCN Journal of Cognitive Neuroscience JCN Journal of Cardiovascular Nursing JCN Journal of Christian Nursing JCN Job Control Number JCN Journal of Child Neurology JCN joint communications network (US DoD) ) - Shin Nippon Biomedical Laboratories (SNBL SNBL Sioux City and New Orleans Barge Line SNBL Snow Blower Unit (on mine trains) ) has obtained new knowledge on cytochrome P450 (CYP CYP In currencies, this is the abbreviation for the Cyprus Pound. Notes: The currency market, also known as the Foreign Exchange market, is the largest financial market in the world, with a daily average volume of over US $1 trillion. ), a drug-metabolizing enzyme, through collaboration with Hokkaido University. Specifically, the two partners have discovered CYP2C76, a molecular species of CYP specifically found in monkeys that have a metabolic pattern similar to human. Further, they have confirmed that CYP2C76 metabolizes drugs and is frequently expressed in the liver. SNBL has already filed application for a patent on these findings. Details of the findings are presented in Molecular Pharmacology, a scientific magazine published by the American Society for Pharmacology and Experimental Therapeutics, under the title "CYP2C76, a novel CYP in cynomolgus monkey, is a major CYP2C in liver, metabolizing tolbutamide tolbutamide /tol·bu·ta·mide/ (tol-bu´tah-mid) a sulfonylurea used as a hypoglycemic in the treatment of type 2 diabetes mellitus; the monosodium salt is used to test for insulinoma and diabetes mellitus. and testosterone". Copyright [c] 2006 Japan Corporate News Network. All rights reserved. |
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