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Shimadzu, Central Research Laboratory to Unveil Protein that Spreads Cancer.


Tokyo, Japan, Apr 25, 2007 - (JCN JCN Japan Corporate News
JCN Journal of Cognitive Neuroscience
JCN Journal of Cardiovascular Nursing
JCN Journal of Christian Nursing
JCN Job Control Number
JCN Journal of Child Neurology
JCN joint communications network (US DoD) 
) - Shimadzu and Central Research laboratory discovered 9 types of protein which showed a marked variation in the numerical value on metastatic cancer. The research used central research laboratory's NOG mouse, an ultra immuno-deficient mouse in implanting human-derived pancreas and colon cancer cells.

The cells were analyzed using Shimadzu's NBS (National Bureau of Standards) See NIST.

NBS - National Bureau of Standards: part of the US Department of Commerce, now NIST.
 reagent, two types of stable isotope reagent which selectively indicates tryptophan tryptophan (trĭp`təfăn), organic compound, one of the 20 amino acids commonly found in animal proteins. Only the l-stereoisomer appears in mammalian protein.  - a type of amino acid in the protein - and proteome pro·te·ome
n.
The complete set of proteins that are produced by the genes of an organism.



proteome

the entire complement of proteins produced by a cell.
 analyzed using NBS biomarker search system. As a result they were able to identify 160 types of protein which showed quantitative fluctuation in the pancreas cancer cells and 150 types in the colon cancer cells.

In a comparative analysis of the two, they detected 9 types of proteins that notably fluctuated in both cancer cells.

Copyright [c] 2007 Japan Corporate News Network. All rights reserved.
COPYRIGHT 2007 Japan Corporate News Network K.K.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2007, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:JCNN News Summaries
Date:Apr 26, 2007
Words:141
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