Series of technical articles describes triple detection GPC/SEC testing.For laboratories involved with characterization of natural and synthetic polymers, proteins or nanoparticulate materials, the company has published a 12-page booket comprising a series of technical articles to help practitioners of triple detection GPC/ SEC better understand and use the technology. Triple detection GPC/SEC is a well-established technique for the accurate and full characterization of macromolecules Macromolecules A large molecule composed of thousands of atoms. Mentioned in: Gene Therapy macromolecules . The technique combines a concentration detector (refractive index A property of a material that changes the speed of light, computed as the ratio of the speed of light in a vacuum to the speed of light through the material. When light travels at an angle between two different materials, their refractive indices determine the angle of transmission or UV-visible), viscometer viscometer Instrument for measuring the viscosity (resistance to internal flow) of a fluid. In one type, the time taken for a given volume of fluid to flow through an opening is recorded. and light scattering detector acting in concert, with each detector providing complimentary but different information. In a single experiment, the triple detection GPC/SEC is said to enable users to obtain molecular weight, molecular size, intrinsic viscosity, conformation con·for·ma·tion n. One of the spatial arrangements of atoms in a molecule that can come about through free rotation of the atoms about a single chemical bond. , structure, branching, aggregation and copolymer copolymer: see polymer. data from their sample. The first article discusses concentration detectors and, in particular, the most commonly used refractive index technique. The second article looks at light scattering detectors and, in particular, provides an authoritative review of the principles of measurement and operation of the low angle light scattering (LALS LALS Latin American Language Services (UK) LALS Low Angle Light Scattering LALS Linkless Ammunition Loading System (Navy) LALS Laser Alarm Locator System ) detector. The third article explores the principles of measurement and operation of the differential viscometer detector. [ILLUSTRATION OMITTED] The booklet concludes that RI, LALS and viscometer detectors working in combination is best. ViscoTek www.viscotek.com |
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